The Axon

"A very nice compendium of current information about axonal histological structure, physiology and pathophysiology. There is an 'all star' cast of authors."--Canadian Journal of Neurological Sciences"The Axon: Structure, Function and Pathophysiology is an excellent addition to the field of axon physiology and pathophysiology. The book is well written and topics are thoroughly covered in a fashion suitable for both basic and clinical neuroscientists. The high-quality illustrations and photomicrographs and the succinct figure legends make it easy for readers to find and understand key points this book should become an important reference forpeople seeking a better understanding of axon biology."--New England Journal of Medicine"The illustrations are outstanding....The photomicrographs of nerves are the best that I have seen....The chapters are heavily referenced, with almost all having citations of articles from 1994 and even, in a chapter or two, 1995. This is unusual and remarkable. The authors have produced an encyclopedic reference book with material that is almost as up-to-date as a journal article....Waxman, Kocsis and Stys have edited an excellent reference volume that isup-to-date and extremely well illustrated. This is the sort of book that should be a standard in neurology and neurosurgery department libraries regardless of academic orientation. For departments ofophthamology and otolaryngology, this book is also a must."--Journal of the American Medical AssociationNoted, not reviewed, in Doody's Journal"An impressive book....with elegant descriptions....There are many stunning freeze-fracture and electron micrographs....The breadth of this book will improve knowledge about the axon for both basic and clinical scientists.This is to be welcomed."--Trends in Neurosciences

• Introduction 1: Sir A. Huxley: Electrical Activity of the Nerve: The Background up to 1952 The Normal Axon 2: C-H. Berthold and M. Rydmark: Morphology of Normal Peripheral Axons 3: A. Hirano and J.F. Llena: Morphology of Central Nervous System Axons 4: J.M. Ritchie: Physiology of Axons 5: N. Kleitman and R.P. Bunge: The Schwann Cell: Morphology and Development 6: J.A. Black, H.W. Sontheimer, and S.G. Waxman: The Oligodendrocyte, The Perinodal Astrocyte, and the Central Node of Ranvier 7: E.S. Monuki and G.E. Lemke: Molecular Biology of Myelination 8: J.L. Salzer: Mechanisms of Adhesion Between Axons and Glial Cells 9: B. Grafstein: Axonal Transport: Function and Mechanisms 10: R.W. Davenport, S. Bolsover, and S.B. Kater: Development of Axons: Calcium, Steering and the Growth Cone 11: S.G. Waxman: Voltaged-gated Ion Channels in Axons: Localization, Function, and Development 12: R.L. Barchi: Molecular Biology of Voltage-dependent Potassium and Sodium Channels 13: W. Vogel and J.R. Schwartz: Voltage-clamp Studies in Axons: Macroscopic and Single Channel Currents 14: J.D. Kocsis and K. Sakatani: Modulation of Axonal Excitability by Neurotransmitter Receptors 15: P.K. Stys, S.G. Waxman, and B.R. Ransom: Ion Pumps and Exchangers 16: H. Bostock: Mechanisms of Accommodation and adaptation in Myelinated Axons 17: P.K. Stys and J.D. Kocsis: Electrophysiological Approaches to the Study of Axons 18: P. Shrager: Action Potential Conduction Recorded Optically in Normal, Demyelinated and Remyelinating Axons Principles of Axonal Pathophysiology 19: G.W. Kreutzberg: Reactiono of the Neuronal Cell Body to Axonal Damage 20: J.W. Griffin, et al.: Axonal Degeneration and Disorders of the Axonal Cytoskeleton 21: J. Rosenbluth: Pathology of Demyelinated and Dysmyelinated Axons 22: S.K. Ludwin: Pathology of the Myelin Sheath 23: S.G. Waxman, J.D. Kocsis, and J.A. Black: Pathophysiology of Demyelinated Axons 24: P.K. Stys, et al.: Anoxic-ischemic Injury in Axons 25: O. Honmou and W. Young: Traumatic Injury of Spinal Axons 26: J.T. Povlshock and C.W. Christman: Diffuse Axonal Injury 27: M. Devor: Abnormal Excitability in Injured Axons 28: M.A. Bisby: Regeneration of PNS Axons 29: L. McKerracher, J.P. Julien, and A.J. Aguayo: Role of Cellular Interactions in Axonal Growth and Regeneration 30: J. Kimura: Clinical Electrophysiology of PNS Axons 31: S.J. Jones: Clinical Assessment of CNS Axons: Evoked Potentials 32: A.R. Berger and H.H. Schaumburg: Human Peripheral Nerve Disease (Peripheral Neuropathies 33: W.I. McDonald: Overview of Clinical Aspects of Multiple Sclerosis, Including Cognitive Deficit 34: M.R. Dimitrijevic: Clinical Aspects of Traumatic Injury to CNS Axons