Neuropsychology of Epilepsy and Epilepsy Surgery

Neuropsychology of Epilepsy and Epilepsy Surgery provides a comprehensive, clinically oriented reference on the neuropsychological assessment and management of patients with epilepsy. The book opens with foundational medical concepts, covering seizure and epilepsy definitions, cellular and network-level mechanisms, the 2025 International League Against Epilepsy (ILAE) classification of seizure types, epilepsy syndromes, and etiology, including structural, genetic, infectious, metabolic, and immune causes. Diagnostic methods are reviewed, including electroencephalography (EEG), structural and functional neuroimaging, and medical treatment with anti-seizure medications (ASMs), the ketogenic diet, and women's reproductive health issues, alongside epilepsy-related mortality. Substantial attention is given to neuropsychological assessment across the lifespan, addressing cognitive deficits, the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE), quality of life, and psychiatric and behavioral comorbidities, including mood, anxiety, psychotic, and personality disorders. A dedicated chapter addresses autoimmune encephalitis and autoimmune epilepsy, and another covers functional/dissociative seizures. The book's second half focuses on epilepsy surgery, detailing presurgical neuropsychological evaluation, lateralization and localization procedures (functional magnetic resonance imaging, the Wada test, and electrical stimulation mapping), resective and disconnective surgical techniques, minimally invasive ablative procedures, and neuromodulation devices. Pediatric considerations are integrated throughout. Case examples illustrate clinical application. Written for neuropsychologists, trainees, and the broader epilepsy care team, this second edition reflects current ILAE classification standards and emerging diagnostic and therapeutic advances in epilepsy and epilepsy surgery.