Diagnostic Pathology: Cardiovascular

Dylan V. Miller is a Professor (Clinical) at the University of Utah School of Medicine's Department of Pathology and is Director of Electron Microscopy and Immunostains at Intermountain Central Laboratory in Salt Lake City, Utah Monica P. Revelo is a Professor at the University of Utah School of Medicine's Department of Pathology, and is Medical Director of Renal and Cardiovascular Pathology at ARUP Laboratories in Salt Lake City, Utah

"This book is the cardiovascular volume from the Elsevier Diagnostic Pathology series. The content spans the full range of cardiovascular conditions, from pericardium, to heart, to blood vessels, addressing both neoplastic and non-neoplastic pathologies. The previous edition was published in 2018." -©Doody’s Review Service, 2024, Catherine S Morris, MD (University of Michigan Medical School)

• SECTION 1: HEART, ENDOMYOCARDIAL BIOPSYCONGENITAL/GENETIC4 Endocardial Fibroelastosis SyndromeMonica P. Revelo, MD, PhD6 Arrhythmogenic CardiomyopathyDylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Monica P. Revelo, MD, PhD12 Fatty Acid Metabolic DisordersMonica P. Revelo, MD, PhD14 Mitochondrial MyopathiesMonica P. Revelo, MD, PhD18 Muscular DystrophiesMonica P. Revelo, MD, PhD22 Glycogen Storage DiseasesMonica P. Revelo, MD, PhD24 Fabry Disease, HeartMonica P. Revelo, MD, PhD28 LAMP2 Mutation (Danon Disease)Jagdish Butany, MBBS, MS, FRCPC, Amar Ibrahim, MB, ChB, MSc, and Monica P. Revelo, MD, PhDACQUIRED30 Amyloid Deposition, HeartElizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD38 Hemochromatosis, HeartPhilippe Romeo, MD and Monica P. Revelo, MD, PhD40 Anthracycline CardiotoxicityBrandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD42 Catecholamine CardiomyopathyMonica P. Revelo, MD, PhD44 Cocaine CardiotoxicityDylan V. Miller, MD and Brian J. Hall, MD46 Immune Checkpoint Inhibitor ToxicityMonica P. Revelo, MD, PhD and Dylan V. Miller, MDINFLAMMATORY50 Lymphocytic MyocarditisMonica P. Revelo, MD, PhD54 Giant Cell MyocarditisBrandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD56 Eosinophilic (Löffler) MyocarditisMonica P. Revelo, MD, PhD60 Sarcoidosis, HeartMonica P. Revelo, MD, PhD62 Acute Rheumatic CarditisMonica P. Revelo, MD, PhD66 Eosinophilic Granulomatosis With PolyangiitisMonica P. Revelo, MD, PhD68 Viral MyocarditisDylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath70 Toxoplasmosis, HeartMonica P. Revelo, MD, PhD72 Chagas Disease, HeartDylan V. Miller, MD and Brian J. Hall, MD76 Lyme Disease and Rickettsial MyocarditisDylan V. Miller, MD and Brian J. Hall, MD80 SARS-CoV-2 (COVID-19)-Related Cardiovascular DiseaseDylan V. Miller, MD and Monica P. Revelo, MD, PhD84 Lupus Erythematosus, HeartMonica P. Revelo, MD, PhDTRANSPLANT REJECTION90 Acute Cellular Transplant Rejection, HeartElizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD96 Antibody-Mediated Transplant Rejection, HeartElizabeth H. Hammond, MD and Monica P. Revelo, MD, PhD102 Quilty LesionsBillie Fyfe, MD and Monica P. Revelo, MD, PhD106 Previous Biopsy Sites, Heart TransplantBillie Fyfe, MD and Monica P. Revelo, MD, PhD108 Posttransplant Lymphoproliferative Disorder, HeartDylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath110 Harvesting Injury/Acute Ischemia, HeartBillie Fyfe, MD and Monica P. Revelo, MD, PhDSECTION 2: HEART, RESECTIONHEART EXPLANT116 Hypertrophic CardiomyopathyVidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD122 Idiopathic Dilated CardiomyopathyDylan V. Miller, MD126 Ischemic Heart DiseaseVidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD130 Overview of Coronary Artery StentsDylan V. Miller, MD134 Cardiac Allograft VasculopathyMonica P. Revelo, MD, PhD140 Radiation Injury, HeartDylan V. Miller, MD and Philippe Romeo, MD142 Cardiac Conduction System DiseaseDylan V. Miller, MD150 Ventricular Assist DevicesDylan V. Miller, MD156 Approach to Cardiomyopathy (Worksheet)Dylan V. Miller, MD158 Approach to Cardiomyopathy DiagnosisDylan V. Miller, MDSECTION 3: HEART, TUMORSBENIGN166 Cardiac MyxomaDylan V. Miller, MD and Joseph J. Maleszewski, MD172 Papillary FibroelastomaDylan V. Miller, MD and Joseph J. Maleszewski, MD176 Cardiac RhabdomyomaDylan V. Miller, MD and Joseph J. Maleszewski, MD180 Cardiac FibromaDylan V. Miller, MD and Joseph J. Maleszewski, MD184 Ectopic Tissues, HeartDylan V. Miller, MD and Joseph J. Maleszewski, MD186 Lipomatous Hypertrophy of Atrial SeptumDylan V. Miller, MD and Billie Fyfe, MDMALIGNANT188 Cardiac LymphomaDylan V. Miller, MD, Brian J. Hall, MD, and Nikhil Sangle, MD, FRCPath190 Cardiac AngiosarcomaJoseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD194 Cardiac Sarcoma, OtherDylan V. Miller, MD and Joseph J. Maleszewski, MD198 Cardiac MetastasesDylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPCSECTION 4: CARDIAC VALVES, NATIVEAORTIC206 Unicommissural Aortic ValveDylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC210 Bicuspid Aortic ValveJagdish Butany, MBBS, MS, FRCPC, Amar Ibrahim, MB, ChB, MSc, and Monica P. Revelo, MD, PhD214 Senile Calcific Aortic StenosisMonica P. Revelo, MD, PhD218 Discrete Membranous Subaortic StenosisDylan V. Miller, MDMITRAL220 Myxomatous Mitral Valve DiseaseDylan V. Miller, MD and Philippe Romeo, MD224 Rheumatic Heart DiseaseDylan V. Miller, MD and Philippe Romeo, MDTRICUSPID228 Carcinoid Heart DiseaseJoseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD232 Ebstein AnomalyDylan V. Miller, MD and Philippe Romeo, MDPULMONARY234 Congenital Pulmonary StenosisDylan V. Miller, MD and Brian J. Hall, MDENDOCARDITIS236 Endocarditis, Native ValveVidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD240 Nonbacterial Thrombotic EndocarditisVidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhDSECTION 5: CARDIAC VALVESPROSTHETIC246 Leaflet Degeneration, Prosthetic ValvesJagdish Butany, MBBS, MS, FRCPC and Monica P. Revelo, MD, PhD250 Thrombosis of Prosthetic ValvesDylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Amar Ibrahim, MB, ChB, MSc252 Endocarditis, Prosthetic ValveDylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC258 Mechanical Heart Valve Prostheses: Modes of FailureDylan V. Miller, MD, Jagdish Butany, MBBS, MS, FRCPC, and Amar Ibrahim, MB, ChB, MSc260 Catheter-Deployed Valve TherapiesDylan V. Miller, MD and Monica P. Revelo, MD, PhDSECTION 6: PERICARDIUMINFLAMMATORY268 Acute PericarditisMonica P. Revelo, MD, PhD272 Constrictive PericarditisMonica P. Revelo, MD, PhD274 Tuberculous PericarditisMonica P. Revelo, MD, PhDTUMORS276 Lymphoma, PericardiumDylan V. Miller, MD278 Metastatic Tumor, PericardiumBillie Fyfe, MD and Monica P. Revelo, MD, PhD282 Mesothelioma, PericardiumDylan V. Miller, MD and Joseph J. Maleszewski, MD286 Mesothelial/Monocytic Incidental Cardiac ExcrescenceDylan V. Miller, MDSECTION 7: VASCULAR DISEASEENDARTERECTOMY/ATHERECTOMY/THROMBECTOMY290 Overview of Peripheral Vascular SpecimensDylan V. Miller, MD and Billie Fyfe, MD296 Thromboembolus, VascularBillie Fyfe, MD and Monica P. Revelo, MD, PhDTHORACIC AORTA300 Aortic Degenerative DiseasesDylan V. Miller, MD and Brandon T. Larsen, MD, PhD308 Genetic Diseases of the AortaJoseph J. Maleszewski, MD and Monica P. Revelo, MD, PhD312 Noninfectious AortitisDylan V. Miller, MD316 Takayasu ArteritisDylan V. Miller, MD320 Aortic DissectionDylan V. Miller, MD and Billie Fyfe, MD324 Aortic CoarctationDylan V. Miller, MD and Monica P. Revelo, MD, PhDABDOMINAL AORTA328 Aortic Atherosclerosis and ComplicationsBillie Fyfe, MD and Monica P. Revelo, MD, PhD334 Chronic Periaortitis and IgG4-Related DiseaseDylan V. Miller, MD336 Mycotic AneurysmMonica P. Revelo, MD, PhDCORONARY ARTERIES340 Atherosclerosis, CoronaryMonica P. Revelo, MD, PhD344 Coronary Artery DissectionMonica P. Revelo, MD, PhD348 Kawasaki DiseaseVidhya Nair, MBBS, MD, FRCPC and Monica P. Revelo, MD, PhD352 Coronary Artery EmboliMonica P. Revelo, MD, PhDTEMPORAL ARTERIES354 Giant Cell/Temporal ArteritisDylan V. Miller, MD and Monica P. Revelo, MD, PhDPERIPHERAL VESSELS358 Buerger Disease (Thromboangiitis Obliterans)Dylan V. Miller, MD and Jagdish Butany, MBBS, MS, FRCPC362 Fibromuscular DysplasiaDylan V. Miller, MD and A. Brad Farris, III, MD368 Segmental Arterial MediolysisDylan V. Miller, MD370 Mönckeberg Medial Calcific SclerosisBrandon T. Larsen, MD, PhD and Monica P. Revelo, MD, PhD372 Behçet DiseaseDylan V. Miller, MD and Brandon T. Larsen, MD, PhD376 Infectious VasculitisDylan V. Miller, MD and Brandon T. Larsen, MD, PhD382 Lymphocytic VenulitisMonica P. Revelo, MD, PhD384 VaricositiesDylan V. Miller, MD and Billie Fyfe, MD386 Hypertensive Renovascular DiseasesDylan V. Miller, MD, A. Brad Farris, III, MD, and Brandon T. Larsen, MD, PhDVASCULAR TISSUE GRAFTS390 Vascular Graft PseudoaneurysmJagdish Butany, MBBS, MS, FRCPC, Pooja Gupta, MBBS, DNB, and Monica P. Revelo, MD, PhDSECTION 8: VASCULAR TUMORSBENIGN396 HemangiomaDylan V. Miller, MD and Brandon T. Larsen, MD, PhD406 AngiomyolipomaDylan V. Miller, MD, Satish K. Tickoo, MD, and Victor E. Reuter, MD410 Glomus TumorDylan V. Miller, MD and Brandon T. Larsen, MD, PhD418 Cystic LymphangiomaMonica P. Revelo, MD, PhD420 Arteriovenous MalformationsDylan V. Miller, MDMALIGNANT424 Epithelioid HemangioendotheliomaDylan V. Miller, MD and Brandon T. Larsen, MD, PhD428 Kaposi SarcomaDylan V. Miller, MD and Brandon T. Larsen, MD, PhD434 AngiosarcomaDylan V. Miller, MD and Brandon T. Larsen, MD, PhDSECTION 9: AUTOPSYCARDIAC442 Coronary Artery Bypass GraftingDylan V. Miller, MD446 Valve Replacement (Including Transcatheter)Dylan V. Miller, MD and Brandon T. Larsen, MD, PhD452 Infective EndocarditisDylan V. Miller, MD458 Ventricular Assist Device InsertionDylan V. Miller, MD and Brandon T. Larsen, MD, PhD462 Heart TransplantDylan V. Miller, MDVASCULAR468 Thoracic Aortic Aneurysm RepairDylan V. Miller, MD, Billie Fyfe, MD, and George P. Batsides, MD474 Abdominal Aortic AneurysmDylan V. Miller, MD and Billie Fyfe, MD478 Cerebral Aneurysm and Vascular MalformationDylan V. Miller, MD and Roy H. Rhodes, MD, PhD