Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 1

Biology and Pathophysiology

AvGanji Purnachandra Nagaraju,Sujatha Peela

Inbunden, Engelska, 2022

1 512 kr

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Beskrivning

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume One: Biology and Pathophysiology provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This volume discusses topics such as tumor microenvironment in hepatocellular carcinoma, endoplasmic reticulum stress and unfolded protein response, effects of cirrhosis and hepatitis on the prognosis of HCC, mitochondrial metabolism, next generation sequencing, and telomerase. In addition, it discusses exosomes role in HCC progression, metastasis and chemokines.

This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer for their research work or clinical setting.

Provides an updated literature review and detailed understanding of liver cancer tumor biology
Discusses abnormal changes in the liver caused, resulting from, or associated with hepatocellular carcinoma from a holistic view
Presents the content with fully colored images and summarizing tables for easy understanding of complex topics

Produktinformation

Utgivningsdatum:2022-02-17
Mått:191 x 235 x undefined mm
Vikt:1 200 g
Format:Inbunden
Språk:Engelska
Antal sidor:386
Förlag:Elsevier Science
ISBN:9780323988063

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Mer om författaren

Dr. Nagaraju obtained his MSc and his PhD, both in Biotechnology, from Sri Venkateswara University in Tirupati, Andhra Pradesh, India. He received his DSc from Berhampur University in Berhampur, Odisha, India. Dr. Nagaraju’s research focuses on translational projects related to gastrointestinal malignancies. He has published over 100 research papers in highly reputed international journals and has presented more than 50 abstracts at various national and international conferences. Dr. Nagaraju is author and editor of several published books for Elsevier and Springer Nature. He serves as editorial board member of several internationally recognized academic journals. Dr. Nagaraju has received several international awards including FAACC. He also holds memberships with the Association of Scientists of Indian Origin in America (ASIOA), the Society for Integrative and Comparative Biology (SICB), The Science Advisory Board, The RNA Society, The American Association for Clinical Chemistry (AACC) and the American Association of Cancer Research (AACR). Dr. Sujatha Peela is full-time Professor in the Department of Biotechnology, Dr. BR Ambedkar University, India. Dr. Peela received her PhD in Biotechnology from Andhra University, and furthermore, she pursued her postdoctoral fellowship from the University of Chicago, USA, in the Department of Medicine. She has published 33 research papers in various highly reputed international journals, attended 84 national and international conferences, and has published 5 books at international level. She received many prestigious awards from government agencies & NGOs. She organized 16 national and international conferences at various platforms in the Biotechnology field. Currently Dr. Peela holds one patent in India.

Innehållsförteckning

1. Cell origin, biology and pathophysiology hepatocellular carcinoma2. Tumor microenvironment in HCC3. Role of endoplasmic reticulum stress and unfolded protein response (UPR) in the onset and progression of hepatocellular carcinoma4. Effect of cirrhosis and hepatitis on the prognosis of hepatocellular carcinoma5. The role of cellular necrosis in hepatocellular carcinoma6. Tyrosine kinases: their role in hepatocellular carcinoma7. Mitochondrial metabolism in the progression of hepatocellular carcinoma8. Role of transcription factors in growth and metastasis in hepatocellular carcinoma9. The role of next generation sequencing in HCC progression10. Functional mechanisms of microRNAs and Long non-coding RNAs in hepatocellular carcinoma11. ROS mediated pathways: Potential role in liver cancer biology and therapy12. Telomerase in hepatocellular carcinoma13. Exosomes role in hepatocellular carcinoma progression and metastasis. An update on the diagnosis of liver cancer14. A review of chemokines in HCC