Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling

Dr. Asim K. Duttaroy is a professor at the Faculty of Medicine, University of Oslo, Oslo, Norway. His research programs focus on the roles of food components on growth and development, as well as in the prevention of diseases such as diabetes and cardiovascular disease. He is also investigating the roles of the antiplatelet and antihypertensive properties of fruits and vegetables. His discoveries of antithrombotic factors in tomatoes and kiwifruits are patented internationally, and three companies (Provexis Limited in the United Kingdom, IDIA AS in Norway, and Genimen Pharmacon in India) are working to commercialize these discoveries. He has published over 265 original contributions and reviews, 6 books, and several book chapters and editorials, and he is the Editor-in-Chief of the journal Food & Nutrition Research, as well as a guest editor of several journals such as Nutrients and Frontiers in Physiology. Dr. Rahul Mallick graduated in medicine from Chittagong University, Bangladesh. He obtained his master’s degree in Medical Biology from Linköping University, Sweden. Currently, he is working as a researcher at the University of Eastern Finland, Finland and his main research interest includes gene expression concerning cardiac remodeling. In addition, he is investigating the issues of regaining cardiac function by introducing an experimental technique that uses genes instead of drugs or surgery to treat or prevent diseases or disorders. He serves as the editorial board member of the peer-reviewed journal Food & Nutrition Research and is collaborating with Prof. Duttaroy on several projects during the last few years.

• 1. Cardiac remodeling: Impacts on cardiac health and disease2. Physiological cardiac modeling: Effects of exercise and other factors3. Prognostic elements of unfavorable cardiac remodeling4. Growth and proliferation of cardiomyocytes: roles of energy metabolism, cell death, oxidative stress, and metabolites5. Cardiac endothelial cells and their cross-talks with neighboring cells in cardiac remodeling6. Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease7. Involvement of cardiac stem cells in cardiac remodeling or myocardial regeneration8. Cardiac pericytes and cardiac remodeling9. Macrophages in the remodeling of diseased heart10. Inflammatory role of neutrophils in cardiac remodeling: damage vs. resolution11. Extracellular vesicle in cardiac remodeling12. Does endoplasmic reticulum stress break the heart?13. Role of pattern recognition receptors in cardiac remodeling14. Junctional adhesion molecules: their roles in integrity and functionality of the heart15. Composition and function of ion channels and their effects in cardiac remodeling16. Cardiokines and cardiac remodeling17. Fatty acids: friend or foe to cardiac remodeling?18. Comparative effects of fatty acid and glucose in cardiac remodeling19. Vitamins, minerals, and nutraceuticals and their cardioprotective function20. NOTCH signaling molecules: a driver of cardiac function21. Wnt signaling: a functional modulator of the heart22. Neuregulin-1: can it be useful to treat heart failure?23. Semaphorins and cardiac conduction system24. Myocardial collagen: Its role in inflammation to interstitial fibrosis25. Myocardial contractile proteins: role in disease progression and drug discovery26. Neurohormones and cardiac remodeling and function27. Regulation and function of the Hippo signaling system in the cardiac pathophysiological process28. Cardiac lymphatic system about myocardial health29. Long non-coding RNAs and microRNAs’ regulatory roles in cardiac disease: an emerging area of research30. Artificial intelligence and cardiac remodeling: emerging ally