Liquid Chromatography

Salvatore Fanali is Director of Research at the Institute of Chemical Methodologies, Italian National Research Council (C.N.R.) in Monterotondo (Rome), Italy, and head of the Capillary Electromigration and Chromatographic Methods Unit at the same Institute. His research activity is mainly focused on separation science including the development of modern miniaturized techniques (electrodriven and liquid chromatography). He also studies hyphenation with mass spectrometry and development of new stationary phases. Separation methods developed are currently applied to food, pharmaceuticals, chiral environment, and biomedical analysis. He is Editor of the Journal of Chromatography A and a member of the advisory editorial board of seven international scientific journals. Fanali is the author of about 300 publications including some book chapters. He received several awards including the “Liberti Medal” in Separation Science from the Italian Chemical Society. Bezhan Chankvetadze is professor of Analytical Chemistry at Tbilisi State University, Editor of Journal of Pharmaceutical and Biomedical Analysis, and is well recognized in the field of separation science. He is one of the leaders in chromatography and chiral separations with a large number of publications. Paul Haddad is currently a Distinguished Professor of Chemistry and Australian Research Council Federation Fellow at the University of Tasmania, as well as Director of the Pfizer Analytical Research Centre. He has more than 500 publications in this field and has presented in excess of 450 papers at local and international scientific meetings. He is an editor of Journal of Chromatography A, a contributing editor for Trends in Analytical Chemistry, and was an editor of Analytica Chimica Acta for 6 years. He is currently a member of the editorial boards of 10 other journals of analytical chemistry or separation science. He is the recipient of several national and international awards, including the ACS Award in Chromatography, the Marcel Golay Award, the AJP Martin Gold Medal awarded by the Chromatographic Society, the Royal Society of Chemistry Analytical Separation Methods Award, the RACI HG Smith and Analytical Division medals, and more. Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography – Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial “International Symposium on High-Performance Thin-Layer Chromatography”. Marja-Liisa Riekkola is a professor of Analytical Chemistry at Helsinki University, Helsinki, Finland. She is well recognized in the field of separation science. She serves as Editor of Journal of Chromatography A. Prof. Riekkola is one of the leaders in chromatography with a large number of publications.

"...the well-structured layout makes it easy for the reader to find the desired information. The written language is clear, the many abbreviations are introduced, and almost all chapters are easy to read…And even though the here-presented volumes cover such a wide range of material, it did not lower the quality or in-depth level of the provided information that one might only expect from a book with a narrower focus...The LC series of the Handbooks in Separation Science lay a great foundation for research purposes and should be declared an essential resource for students aiming to work with liquid chromatographic techniques. Having all the information organized in one spot is additionally useful for researchers already active in the field." --Claudia Zielke, Springer

• 1. Milestones in the development of liquid chromatography2. Kinetic theories of liquid chromatography3. Column technology in liquid chromatography4. General instrumentation in HPLC5. Liquid-solid chromatography6. Reversed-phase liquid chromatography7. Secondary chemical equilibria in reversed-phase liquid chromatography8. Ultra-high performance and Ultrafast liquid chromatography9. Nano-liquid chromatography10. Hydrophilic interaction liquid chromatography11. Mobile phase selection in liquid chromatography12. Co-solvents and mobile phase additives (new chapter)13. Method development in liquid chromatography 14. Physicochemical measurements15. Theory and practice of gradient elution liquid chromatography16. Fundamentals of Enantioselective LC (Chiral recognition mechanisms)17. Hydrophobic interaction chromatography18. Ion chromatography19. Size-exclusion chromatography20. Interaction polymer chromatography21. Affinity chromatography22. Multidimensional Liquid Chromatography23. Process concepts in preparative chromatography24. Modeling of preparative liquid chromatography25. Capillary electrochromatography26. Liquid Chromatography on microchip27. Mass spectrometric detection, instrumentation and ionization methods28. Identification and quantitation in Mass Spectrometry29. Advanced IR and Raman detectors for identification and quantification30. Advanced spectroscopic detectors for identification and quantification: Nuclear magnetic resonance31. Prediction of retention in Liquid Chromatography32. Validation of liquid chromatographic methods – chemometrics and calibration