Mariacarla Gadebusch Bondio is Professor in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyFrancesco Spöring is Research Assistant in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyJohn-Stewart Gordon is Professor of Philosophy and Head of the Applied Ethics Research Group at Vytautas Magnus University, Lithuania

• Introduction: Predictive Medicine – An Interdisciplinary ApproachMariacarla Gadebusch Bondio, Francesco Spöring, and John-Stewart GordonPart I. Individual Challenges1. Beyond the Causes of Disease: Prediction and the Need for a New Philosophy of MedicineMariacarla Gadebusch Bondio2. Comprehending and Communicating Statistics in Breast Cancer Screening. Ethical Implications and Potential SolutionsGiulia Ferretti, Alma Linkeviciute, and Giovanni Boniolo3. On the Nature of the Right Not to KnowJohn-Stewart Gordon4. Predictive Diagnostic Testing for Late-Onset Neurological Diseases in Asymptomatic Minors: ‘Do No Harm’ and the Value of KnowledgeHeiner Fangerau, Florian Braune, and Christian Lenk5. Incidental Findings in Genetic TestingElke Holinski-Feder and Verena Steinke-LangePart II. Social Challenges6. Risk and Solidarity within Individualized MedicineKonrad Ott7. Anticipatory Medicalization: Predisposition, Prediction, and Proto-Disease, Expanding Medicalized ConditionsPeter Conrad and Miranda Waggoner8. Predicting the Cost of Diseases in Resource-Poor CountriesSteffen Flessa9. Genetic Disorders in Chinese Patients and Their Families: A Call for Action on Predictive MedicineXian-Ning Zhang and Ji ZuoPart III. Research Challenges10. Personalized Antidepressant Prescription: A Historical Perspective on Risks and OpportunitiesFrancesco Spöring11. Predicting, Preventing, and Treating Alzheimer’s Disease: Current State and Future ChallengesStefan F. Lichtenthaler12. Early Detection, Prediction, and Prognosis of Alzheimer’s DiseaseSimone Lista, Francesco Garaci, Nicola Toschi, and Harald Hampel13. Immunoscore, Circulating Tumor Cells and Human-Derived Organoids as Potential Predictive Tools in Personalized Cancer MedicineAgnieszka Pastuła

Mariacarla Gadebusch Bondio is Professor in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyFrancesco Spöring is Research Assistant in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyJohn-Stewart Gordon is Professor of Philosophy and Head of the Applied Ethics Research Group at Vytautas Magnus University, Lithuania

• Introduction: Predictive Medicine – An Interdisciplinary ApproachMariacarla Gadebusch Bondio, Francesco Spöring, and John-Stewart GordonPart I. Individual Challenges1. Beyond the Causes of Disease: Prediction and the Need for a New Philosophy of MedicineMariacarla Gadebusch Bondio2. Comprehending and Communicating Statistics in Breast Cancer Screening. Ethical Implications and Potential SolutionsGiulia Ferretti, Alma Linkeviciute, and Giovanni Boniolo3. On the Nature of the Right Not to KnowJohn-Stewart Gordon4. Predictive Diagnostic Testing for Late-Onset Neurological Diseases in Asymptomatic Minors: ‘Do No Harm’ and the Value of KnowledgeHeiner Fangerau, Florian Braune, and Christian Lenk5. Incidental Findings in Genetic TestingElke Holinski-Feder and Verena Steinke-LangePart II. Social Challenges6. Risk and Solidarity within Individualized MedicineKonrad Ott7. Anticipatory Medicalization: Predisposition, Prediction, and Proto-Disease, Expanding Medicalized ConditionsPeter Conrad and Miranda Waggoner8. Predicting the Cost of Diseases in Resource-Poor CountriesSteffen Flessa9. Genetic Disorders in Chinese Patients and Their Families: A Call for Action on Predictive MedicineXian-Ning Zhang and Ji ZuoPart III. Research Challenges10. Personalized Antidepressant Prescription: A Historical Perspective on Risks and OpportunitiesFrancesco Spöring11. Predicting, Preventing, and Treating Alzheimer’s Disease: Current State and Future ChallengesStefan F. Lichtenthaler12. Early Detection, Prediction, and Prognosis of Alzheimer’s DiseaseSimone Lista, Francesco Garaci, Nicola Toschi, and Harald Hampel13. Immunoscore, Circulating Tumor Cells and Human-Derived Organoids as Potential Predictive Tools in Personalized Cancer MedicineAgnieszka Pastuła

Mariacarla Gadebusch Bondio is Professor in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyFrancesco Spöring is Research Assistant in the Institute for History and Ethics of Medicine at Technical University of Munich, GermanyJohn-Stewart Gordon is Professor of Philosophy and Head of the Applied Ethics Research Group at Vytautas Magnus University, Lithuania

• Introduction: Predictive Medicine – An Interdisciplinary ApproachMariacarla Gadebusch Bondio, Francesco Spöring, and John-Stewart GordonPart I. Individual Challenges1. Beyond the Causes of Disease: Prediction and the Need for a New Philosophy of MedicineMariacarla Gadebusch Bondio2. Comprehending and Communicating Statistics in Breast Cancer Screening. Ethical Implications and Potential SolutionsGiulia Ferretti, Alma Linkeviciute, and Giovanni Boniolo3. On the Nature of the Right Not to KnowJohn-Stewart Gordon4. Predictive Diagnostic Testing for Late-Onset Neurological Diseases in Asymptomatic Minors: ‘Do No Harm’ and the Value of KnowledgeHeiner Fangerau, Florian Braune, and Christian Lenk5. Incidental Findings in Genetic TestingElke Holinski-Feder and Verena Steinke-LangePart II. Social Challenges6. Risk and Solidarity within Individualized MedicineKonrad Ott7. Anticipatory Medicalization: Predisposition, Prediction, and Proto-Disease, Expanding Medicalized ConditionsPeter Conrad and Miranda Waggoner8. Predicting the Cost of Diseases in Resource-Poor CountriesSteffen Flessa9. Genetic Disorders in Chinese Patients and Their Families: A Call for Action on Predictive MedicineXian-Ning Zhang and Ji ZuoPart III. Research Challenges10. Personalized Antidepressant Prescription: A Historical Perspective on Risks and OpportunitiesFrancesco Spöring11. Predicting, Preventing, and Treating Alzheimer’s Disease: Current State and Future ChallengesStefan F. Lichtenthaler12. Early Detection, Prediction, and Prognosis of Alzheimer’s DiseaseSimone Lista, Francesco Garaci, Nicola Toschi, and Harald Hampel13. Immunoscore, Circulating Tumor Cells and Human-Derived Organoids as Potential Predictive Tools in Personalized Cancer MedicineAgnieszka Pastuła