GHRH, GH, and IGF-I

Basic and Clinical Advances

AvM. R. Blackman,Serono Symposia USA

Inbunden, Engelska, 1995

Del i serien Serono Symposia USA

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Beskrivning

This volume contains the proceedings of the Symposium on GHRH, GH, and IGF-1: Basic and Clinical Advances, held December 9 - 12, 1993 in San Diego, California. Written and edited by eminent international experts, the papers herein cover: an overview of the physiology of GHRH-Somatostatin-GH-IGF-1 axis; the effects of recombinant human GH and/or IGF-1 in catabolic illness; contemporary issues in growth and development; the effects of rhGH and IGF-1 on intermediary and bone metabolism; and the use of GHRH, rhGH, and rhIGF-1 in aging.

Produktinformation

Utgivningsdatum:1995-06-02
Mått:155 x 235 x 24 mm
Vikt:688 g
Format:Inbunden
Språk:Engelska
Serie:Serono Symposia USA
Antal sidor:319
Upplaga:1995
Förlag:Springer-Verlag New York Inc.
ISBN:9780387944043

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Endokrinologi inom Medicin

Innehållsförteckning

I. Overview of Physiology of the GHRH-Somatostatin-GH-IGF-I Axis.- 1. Physiology of the Growth Hormone Releasing Hormone-Somatostatin-Growth Hormone-Insulin-Like Growth Factor I Axis.- 2. Role of Somatostatin in the Regulation of Growth Hormone Secretion.- 3. Growth Hormone Releasing Hormone and Growth Hormone Releasing Peptides.- 4. GH Binding Protein, GH Receptors, and Domains Involved in Signal Transduction.- 5. Insulin-Like Growth Factors During Development.- II. Effects of Recombinant Human GH and/or IGF-I in Catabolic Illness.- 6. Anabolic Effects of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Human Disease.- 7. Growth Hormone in Children with Chronic Renal Disease: Some Metabolic Considerations.- 8. Growth Hormone: The Visible Difference in Burn Care.- 9. Effects of Recombinant Human Growth Hormone on Body Composition and Metabolism in HIV-Associated Wasting.- 10. Administration of Growth Hormone as an Adjunct to Nutritional Support in Critical Illness.- 11. Strategies for the Use of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Amyotrophic Lateral Sclerosis.- III. Contemporary Issues in Growth and Development.- 12. Contemporary Issues in Growth and Development: An Overview.- 13. Use of Recombinant IGF-I in Syndromes of GH Insensitivity.- 14. Use of Growth Hormone in Non-Growth-Hormone-Deficient Children: Physiologic, Pharmacologic, and Ethical Issues.- 15. Growth Hormone Treatment of Nonelderly Adults with GH Deficiency.- IV. Effects of rhGH and IGF-I on Intermediary and Bone Metabolism.- 16. Overview of Growth Hormone and IGF-I Effects on Intermediary Metabolism and Bone.- 17. Effects of rhGH on Glucose, Lipid, and Amino Acid Metabolism.- 18. Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus.- 19. Modulation of Responses to GH and IGF-I by Nutritional Variables.- 20. Growth Hormone Effects on the Adult Skeleton.- 21. Insulin-Like Growth Factors and Skeletal Remodeling.- V. Use of GHRH, rhGH, and rhIGF-I in Aging.- 22. Growth Hormone and Aging: A Brief Review.- 23. Potential Benefits and Risks in Treating the Hyposomatomedinemia and Hypogonadism of Elderly Men.- 24. Effects of Growth Hormone Releasing Hormone Administration in Healthy Aging Men.- 25. Effects of Recombinant Human Insulin-Like Growth Factor I in Aging.- 26. Growth Hormone and Immune Function in the Elderly.- 27. Treatment with Growth Hormone: Focus on Specificity with a View to the Future.- Author Index.