Metabolomic Phenotyping for the Future of Personalized Medicine

Beyond the Biomarkers

Häftad, Engelska, 2026

1 932 kr

Kommande

Beskrivning

Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis-from sample collection to data interpretation-while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.

The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

Describes the basic principles of systems biology and the role of metabolomics
Explains the basic principles of metabolomics experimentation in terms of both experimental design and laboratory analysis
Details the main uses of metabolomics profiling for the diagnosis and prognosis of major human diseases and how it can be applied in the study of various diseases
Analyzes and outlines the European and US regulatory frameworks regarding the use of artificial intelligence technologies, and in particular, machine learning in public health

Produktinformation

Utgivningsdatum:2026-09-30
Mått:191 x 235 x undefined mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Antal sidor:460
Förlag:Elsevier Science
ISBN:9780443236778

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Mer om författaren

Author of more than 100 papers in international peer-reviewed journals, holder of several international patents, and speaker at dozen international conferences, Jacopo Troisi is an award-winning expert in the metabolomics field. After graduating Summa cum Laude in biotechnology, he joined Medical School in the prestigious “Scuola Medica Salernitana at the University of Salerno (Italy). He also attended and completed studies in data analysis. Currently, he is a visiting professor of Metabolomics in both Salerno and Sannio Universities (Italy), cofounder and CEO at Theoreo Srl, spin-off company of the University of Salerno, and COO at the European Biomedical Research Institute of Salerno (EBRIS). His research interests are mainly focused on metabolomic profiling to provide insights in human disease onset and for the development of diagnostic tools. Martina Lombardi is currently serves as Chief Scientific Officer at Theoreo srl, a spin-off company of the University of Salerno that deals with metabolomics, specifically the use of metabolomic profiling for the development of screening tests for human diseases. She also works at the “AOU Ruggi D'aragona University Hospital in Salerno, Italy, where she was awarded a fellowship in internal medicine to study specifically the mechanisms underlying the progression of non-alcoholic fatty liver disease (NAFLD) and its association with metabolic syndrome and cardiovascular risk. She has published various papers in international peer-reviewed journals and presented her research results at metabolomic and bioinformatics and computational biology international conferences. She is currently actively engaged in the development of screening tests based on metabolomic profiling for various diseases, focusing mainly on oncological diseases and is part of the scientific committee of a national conference on applications of metabolomic profiling in endometrial cancer screening.

Innehållsförteckning

1. Metabolomics in system biology2. The metabolomics workflow: Fundamentals of chemical analysis3. Data analysis approaches in untargeted metabolomics4. Targeted metabolomics in investigating human diseases5. Biomarker discovery: Pros and cons6. Metabolomic profiling in screening and prognosis7. Personalized medicine approaches: Interpreting the metabolome8. Prenatal medicine: Metabolomics contribution and future targets9. Metabolomics in the study of autoimmune diseases: Evidence and perspectives10. From neurodevelopmental to neurodegenerative disorders: Insights from the metabolome lens11. Cancer metabolomics: Is cancer a metabolic disease?12. International normative aspects13. Future perspectives