Drug Targeting Complexity
Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy
AvLalit Kumar,Dalapathi Gugulothu
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Beskrivning
Each chapter meticulously evaluates key regulatory molecules such as TGF-?, CTLA-4, and IL-10, exploring their roles in tumorigenesis and the potential for targeted interventions across a spectrum of malignancies. Subsequent sections focus on tumor tissue-specific molecular targets, encompassing immunological checkpoints, growth factors, and signaling pathways pertinent to cancers of the liver, stomach, ovary, prostate, and colon. The text provides insights into the application of monoclonal antibodies and molecular inhibitors as strategies to impede cancer progression and address therapeutic resistance. Concluding chapters address emerging therapeutic paradigms, including precision medicine and nanotechnology.
- Offers comprehensive insights into tissue-specific and tumor-specific molecular targets for cancer therapy
- Explores novel therapeutic strategies to enhance precision medicine in oncology
- Discusses the critical mediators that influence tumor immunity and therapeutic interventions
- Highlights advanced approaches, including nanotechnology, for improved drug delivery systems
- Provides practical applications for targeted therapies to optimize patient outcomes