Advanced Biomaterials

BIKRAMJIT BASU, PhD, is an Associate Professor in the Department of Materials and Metallurgical Engineering at the Indian Institute of Technology Kanpur. His research interests include ceramic and polymer-based biocompatible materials, nanoceramics and nanoceramic composites, and tribology of advanced materials. He received the Coble Award of the American Ceramic Society in 2008 and was recognized by the Indian National Science Academy and the Indian National Academy of Engineering.DHIRENDRA S. KATTI, PhD, is an Associate Professor in the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology Kanpur. His research interests include polymeric biomaterials, drug delivery systems, tissue engineering, and nanotechnology.ASHOK KUMAR, PhD, is an Associate Professor in the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology Kanpur. His research interests include the design of supermacroporous polymeric materials and smart polymers for application in tissue engineering, development of cell separation technology, extracorporeal medical devices, and high-throughput analysis. His other research interests include bioprocess engineering, biosensors, and environmental biotechnology.

• Foreword (by Prof. Larry L. Hench) ixPreface xiContributors xvAbout the Editors xxiSection I1 Fundamentals of Biomaterials And Biocompatibility 3Bikramjit Basu and Shekhar Nath2 Fundamentals of Hydroxyapatite and Related Calcium Phosphates 19Racquel Zapanta LeGeros, Atsuo Ito, Kunio Ishikawa, Toshiro Sakae, and John P. LeGeros3 Materials for Orthopedic Applications 53Shekhar Nath and Bikramjit Basu Copyrighted Material4 the Micro Macroporous Biphasic Calcium Phosphate Concept for Bone Reconstruction and Tissue Engineering 101Guy Daculsi, Franck Jegoux, and Pierre Layrolle5 Science and Technology Integrated Titanium Dental Implant Systems 143Yoshiki Oshida and Elif Bahar Tuna6 Injectable Hydrogels as Biomaterials 179Lakshmi S. Nair, Cato T. Laurencin, and Mayank Tandon7 Nanomaterials for Improved Orthopedic and Bone Tissue Engineering Applications 205Lijie Zhang, Sirinrath Sirivisoot, Ganesh Balasundaram, and Thomas J. WebsterSection II8 Introduction to Processing of Biomaterials 245Dhirendra S. Katti, Shaunak Pandya, Meghali Bora, and Rakesh Mahida9 Laser Processing of Orthopedic Biomaterials 277Rajarshi Banerjee and Soumya Nag10 Functionally Graded All Ceramic Hip Joint 323Omer Van der Biest, Guy Anné, Kim Vanmeensel, and Jef Vleugels11 Medical Devices Based on Bioinspired Ceramics 357Pío González, Julián Martínez-Fernández, Antonio R. de Arellano-López, and Mrityunjay Singh12 Ionomer Glasses: Design and Characterization 411Artemis Stamboulis and Fei Wang13 Designing Nanofibrous Scaffolds for Tissue Engineering 435Neha Arya, Poonam Sharma, and Dhirendra S. Katti14 Design of Supermacroporous Biomaterials Via Gelation at Subzero Temperatures—cryogelation 499Fatima M. Plieva, Ashok Kumar, Igor Yu. Galaev, and Bo MattiassonSection III15 Biomaterial Applications 535Ashok Kumar, Akshay Srivastava, and Era Jain16 Cell-based Nanocomposites and Biomolecules For Bone Tissue Engineering 551Michelle Ngiam, Susan Liao, Casey Chan, and S. Ramakrishna17 Orthopedic Interface Tissue Engineering: Building The Bridge to Integrated Musculoskeletal Tissue Systems 589Helen H. Lu, Kristen L. Moffat, and Jeffrey P. Spalazzi18 Cells of the Nervous System and Electrical Stimulation 613Carlos Atico Ariza and Surya K. Mallapragada19 Placental Umbilical Cord Blood: a True Blood Substitute 643Niranjan Bhattacharya20 Supported Cell Mimetic Monolayers and Their Blood Compatibility 663K. Kaladhar and Chandra P. Sharma21 Titanium Nitride and Diamond Like Carbon Coatings for Cardiovascular Applications 677C.V. Muraleedharan and G.S. BhuvaneshwarIndex 707