"...represents a very interesting and curious aspect of the exploration of situations resulting from the biological effects of human isolation and migration. These investigations may particularly help to understand and to elucidate a variety of biological problems ranging from evolutionary change to the etiology of the diseases....A real book to meditate." Cellular and Molecular Biology

• Preface; 1. The legacy of the IBP - Presidential Address N. Fujiki; 2. The distinction between primary and secondary isolates J. V. Neel; 3. Time trends in the break-up of isolates T.Yanase; 4. Factors influencing the frequency of consanguineous marriages in Japan Y. Imaizumi; 5. Break-up of isolates F. Vogel; 6. Isolates in India, their origin and characterisation K. C. Malhotra; 7. Consanguineous marriages and their genetical consequences in some Indian populations D. P. Mukherjee; 8. Biomedical and immunogenetic variation in isolated populations in India S. S. Papiha; 9. Genetic distance analyses in Israeli groups using classical markers and DNA polymorphisms in the B globin gene B. Bonné-Tamir, A. Zoossmann-Diskin, A. Ticher, A. Oppenheim and S. Nevo; 10. Non random distribution of Gm haplotypes in northern Siberia R. I. Sukernik; 11. Allele frequency estimation N. Yasuda; 12. Genetic affinities of human populations N. Saitou, K. Tokunaga and K. Omoto; 13. Inherited neurological diseases in southern Japan K. Kondo; 14. Serological and virological evidence for human T-lymphotropic virus type 1 infection among the isolated Hagahai of Papua New Guinea R. Yanagihara and R. M. Garruto; 15. Analysis of genes associated with hypercholesterolaemia in the Japanese population H. Hamaguchi, Y. Watanabe, Y. Yamanouchi, H. Yanagi, T. Arinami, R. Miyazaki, S. Tsuchiya and K. Kobayshi; 16. Migrant studies and their problems P. T. Baker; 17. Tokelau: migration and health in a small Polynesian society a longitudinal study I. Prior; 18. Micromigrations of isolated Tureg tribes of the Sahara Desert P. Lefevre-Witier; 19. Population structure in the eastern Adriatic: the influence of historical processes, migration patterns, isolation and ecological pressures, and their interaction P. Rudan, A Sujoldzic, D. Simic, L. A. Bennett and D. F. Roberts; 20. Diabetes and diabetic macroangiopathy in Japanese-Americans H. Hara, G. Egusa, K. Yamane and M. Yamakido; 21. Diabetes and westernisation in Japanese migrants Y. Kanazawa, M. Iunes and W. Fujimoto; 22. Environmental factors affecting ischemic heart disease G. Mimura, K. Murakami, M. Gushiken and S. Ogawa; Epilogue D. F. Roberts.

"...represents a very interesting and curious aspect of the exploration of situations resulting from the biological effects of human isolation and migration. These investigations may particularly help to understand and to elucidate a variety of biological problems ranging from evolutionary change to the etiology of the diseases....A real book to meditate." Cellular and Molecular Biology

• Preface; 1. The legacy of the IBP - Presidential Address N. Fujiki; 2. The distinction between primary and secondary isolates J. V. Neel; 3. Time trends in the break-up of isolates T.Yanase; 4. Factors influencing the frequency of consanguineous marriages in Japan Y. Imaizumi; 5. Break-up of isolates F. Vogel; 6. Isolates in India, their origin and characterisation K. C. Malhotra; 7. Consanguineous marriages and their genetical consequences in some Indian populations D. P. Mukherjee; 8. Biomedical and immunogenetic variation in isolated populations in India S. S. Papiha; 9. Genetic distance analyses in Israeli groups using classical markers and DNA polymorphisms in the B globin gene B. Bonné-Tamir, A. Zoossmann-Diskin, A. Ticher, A. Oppenheim and S. Nevo; 10. Non random distribution of Gm haplotypes in northern Siberia R. I. Sukernik; 11. Allele frequency estimation N. Yasuda; 12. Genetic affinities of human populations N. Saitou, K. Tokunaga and K. Omoto; 13. Inherited neurological diseases in southern Japan K. Kondo; 14. Serological and virological evidence for human T-lymphotropic virus type 1 infection among the isolated Hagahai of Papua New Guinea R. Yanagihara and R. M. Garruto; 15. Analysis of genes associated with hypercholesterolaemia in the Japanese population H. Hamaguchi, Y. Watanabe, Y. Yamanouchi, H. Yanagi, T. Arinami, R. Miyazaki, S. Tsuchiya and K. Kobayshi; 16. Migrant studies and their problems P. T. Baker; 17. Tokelau: migration and health in a small Polynesian society a longitudinal study I. Prior; 18. Micromigrations of isolated Tureg tribes of the Sahara Desert P. Lefevre-Witier; 19. Population structure in the eastern Adriatic: the influence of historical processes, migration patterns, isolation and ecological pressures, and their interaction P. Rudan, A Sujoldzic, D. Simic, L. A. Bennett and D. F. Roberts; 20. Diabetes and diabetic macroangiopathy in Japanese-Americans H. Hara, G. Egusa, K. Yamane and M. Yamakido; 21. Diabetes and westernisation in Japanese migrants Y. Kanazawa, M. Iunes and W. Fujimoto; 22. Environmental factors affecting ischemic heart disease G. Mimura, K. Murakami, M. Gushiken and S. Ogawa; Epilogue D. F. Roberts.

"...represents a very interesting and curious aspect of the exploration of situations resulting from the biological effects of human isolation and migration. These investigations may particularly help to understand and to elucidate a variety of biological problems ranging from evolutionary change to the etiology of the diseases....A real book to meditate." Cellular and Molecular Biology

• Preface; 1. The legacy of the IBP - Presidential Address N. Fujiki; 2. The distinction between primary and secondary isolates J. V. Neel; 3. Time trends in the break-up of isolates T.Yanase; 4. Factors influencing the frequency of consanguineous marriages in Japan Y. Imaizumi; 5. Break-up of isolates F. Vogel; 6. Isolates in India, their origin and characterisation K. C. Malhotra; 7. Consanguineous marriages and their genetical consequences in some Indian populations D. P. Mukherjee; 8. Biomedical and immunogenetic variation in isolated populations in India S. S. Papiha; 9. Genetic distance analyses in Israeli groups using classical markers and DNA polymorphisms in the B globin gene B. Bonné-Tamir, A. Zoossmann-Diskin, A. Ticher, A. Oppenheim and S. Nevo; 10. Non random distribution of Gm haplotypes in northern Siberia R. I. Sukernik; 11. Allele frequency estimation N. Yasuda; 12. Genetic affinities of human populations N. Saitou, K. Tokunaga and K. Omoto; 13. Inherited neurological diseases in southern Japan K. Kondo; 14. Serological and virological evidence for human T-lymphotropic virus type 1 infection among the isolated Hagahai of Papua New Guinea R. Yanagihara and R. M. Garruto; 15. Analysis of genes associated with hypercholesterolaemia in the Japanese population H. Hamaguchi, Y. Watanabe, Y. Yamanouchi, H. Yanagi, T. Arinami, R. Miyazaki, S. Tsuchiya and K. Kobayshi; 16. Migrant studies and their problems P. T. Baker; 17. Tokelau: migration and health in a small Polynesian society a longitudinal study I. Prior; 18. Micromigrations of isolated Tureg tribes of the Sahara Desert P. Lefevre-Witier; 19. Population structure in the eastern Adriatic: the influence of historical processes, migration patterns, isolation and ecological pressures, and their interaction P. Rudan, A Sujoldzic, D. Simic, L. A. Bennett and D. F. Roberts; 20. Diabetes and diabetic macroangiopathy in Japanese-Americans H. Hara, G. Egusa, K. Yamane and M. Yamakido; 21. Diabetes and westernisation in Japanese migrants Y. Kanazawa, M. Iunes and W. Fujimoto; 22. Environmental factors affecting ischemic heart disease G. Mimura, K. Murakami, M. Gushiken and S. Ogawa; Epilogue D. F. Roberts.