Peptide Antibiotics

Discovery Modes Of Action And Applications

Inbunden, Engelska, 2001

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Beskrivning

This reference summarizes the latest research on the structure, function, and design of synthetic and natural peptide antibiotics, describing practical applications of these compounds in food preservation and packaging, and in the prevention and treatment of infectious diseases by direct anti-bacterial action and as part of the adaptive immune response.Peptide Antibiotics discusses these unique compounds and their many and exciting applications, including: the distribution and classification of diverse antimicrobial peptides throughout nature the role in host defense of mucosal surface peptide antibiotics such as defensins and cathepsins the biosynthesis of lanthionine-containing antibiotics including nisin, epidermin, and mersacidin the genetic basis determining the production of bacterial peptide antibiotics the potential commercial use of magainin, nisin, and lacticin peptides as anti-infective agents the use of nisin as a commercial food preservative With contributions from 19 world-renowned experts in the field, Peptide Antibiotics is an indispensable source of information for pharmaceutical scientists, medicinal and organic chemists and biochemists, microbiologists, infectious disease specialists, molecular biologists, and upper-level undergraduate and graduate students in these disciplines.

Produktinformation

Utgivningsdatum:2001-12-04
Mått:152 x 229 x undefined mm
Vikt:730 g
Format:Inbunden
Språk:Engelska
Antal sidor:308
Förlag:Taylor & Francis Inc
ISBN:9780824702458

Utforska kategorier

Kemi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Tillverkningsteknik inom Naturvetenskap och teknik

Mer om författaren

Christopher J. Dutton is Senior Principal Scientist, Pfizer Global Research and Development, Sandwich, Kent, England. He is a Fellow of the Royal Society of Chemistry and a member of the Society for Medicines Research. Dr. Dutton received the Ph.D. degree (1983) from Cambridge University, England. Mark A. Haxell is Licensing Coordinator, Pfizer Global Research and Development, Sandwich, Kent, England. A member of the Licensing Executives Society, he received the Ph.D. degree (1983) in microbiology from Liverpool John Moores University, Liverpool, England. Hamish A. I. McArthur is Assistant Director, Bioprocess Research and Development, Pfizer Global Research, Groton, Connecticut. A member of the Society for General Microbiology and the American Society for Microbiology, Dr. McArthur received the Ph.D. degree (1975) in microbial biochemistry from St. John's College, University of Cambridge, England. Richard G. Wax is Principal Research Investigator, Pfizer Global Research, Groton, Connecticut. He is a member of the American Society for Microbiology and the Society for Industrial Microbiology. Dr. Wax received the Ph.D. degree (1963) in biophysics from the Pennsylvania State University, University Park.

Innehållsförteckning

Introduction to the Peptide AntibioticsHarry W. TaberSources of Antimicrobial PeptidesChemistry and Applications of Synthetic Antimicrobial PeptidesDavid Andreu and Luis RivasLanthionine-Containing Bacterial PeptidesUlrike Pag and Hans-Georg SahlUnmodified Peptide-Bacteriocins (Class II) Produced by Lactic Acid BacteriaIngolf F. Nes, Helge Holo, Gunnar Fimland, Håvard Hildeng Hauge, and Jon Nissen-MeyerInsect Cationic Antimicrobial PeptidesCharles Hetru, Jules A. Hoffmann, and Robert E. W. HancockMammalian Antimicrobial PeptidesCharles L. Bevins and Gill DiamondPotential Applications of PeptidesExploitation of Lantibiotic Peptides for Food and Medical UsesMáire P. Ryan, Colin Hill, and R. Paul RossAmphibian Antimicrobial PeptidesMichael A. ZasloffIndex