Integrated Microfabricated Biodevices

Advanced Technologies for Genomics, Drug Discovery, Bioanalysis, and Clinical Diagnostics

Inbunden, Engelska, 2002

2 954 kr

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Beskrivning

This book discusses the new generation of integrated microfabricated devices, including DNA chips, Lab-on-a-Chip, microcapillary electrophoresis systems, biosensors, and microanalytical systems. It traces their development with the established and evolving technologies such as microlithography, micromachining, microelectromechanical systems, microfluids, and nanotechnology.

Produktinformation

Utgivningsdatum:2002-01-03
Mått:210 x 280 x undefined mm
Vikt:725 g
Format:Inbunden
Språk:Engelska
Antal sidor:464
Förlag:Taylor & Francis Inc
ISBN:9780824706067

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Michael J. Heller, Andras Guttman

Innehållsförteckning

Towards integrated electrophoretic microdevice for clinical diagnostics; creating a lab-on-a-chip with microfluidic technologies; Short Tandem Repeat (STR) analysis on microfabricated electrophoretic devices; basic sample preparation - DNA separation and purification; multiplex integrated online sample preparation for DNA sequencing and genetic typing; interfacing capillaries to microseparation devices for sample introduction; electric field meditated separation of DNA fragments on planar gel microchips; development of battery powered, portable instrumentation for rapid PCR analysis; practical aspects of sheath flow fraction collection in CE; microelectric array systems for DNA diagnostic and pharmacogenomic applications; the flowthru chip - a miniature, three-dimensional biochip platform; DNA arrays on plastic devices; microfluidic devices fabricated by polymer hot embossing; microfabricated reactor technology; approaches toward miniaturization of high throughput screening of chemical libraries; integrated microsystems in clinical chemistry - constraints and consequences.