Duchenne Muscular Dystrophy

Advances in Therapeutics

AvJeffrey S. Chamberlain,Thomas A. Rando

Inbunden, Engelska, 2006

Del i serien Neurological Disease and Therapy

3 474 kr

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Beskrivning

Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art contributions on pharmacological interventions, regenerative medicine, and gene therapy.

Produktinformation

Utgivningsdatum:2006-02-27
Mått:152 x 229 x 31 mm
Vikt:793 g
Format:Inbunden
Språk:Engelska
Serie:Neurological Disease and Therapy
Antal sidor:496
Förlag:Taylor & Francis Inc
ISBN:9780824723255

Utforska kategorier

Medicinsk genetik inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin
Genterapi inom Medicin

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Jeffrey S. Chamberlain, Thomas A. Rando

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Innehållsförteckning

Clinical Overview. The Functional Biology of Dystrophin. Duchenne Muscular Dsytrophy and Becker Muscular Dystrophy: Diagnostic Principles. Mutation Detection. Protein Studies. Medical Management. Rehabilitation Management. A Review of Current Practice and Clinical Outcomes. Therapeutic Principles and Challenges. Experimental Pharmacologic Therapies. Utrophin: The Intersection between Pharmacological and Genetic Therapy. Regenerative Therapy. Cellular-Mediated Delivery: The Intersection between Regenerative Medicine and Genetic Therapy. Oligonucleotide-Mediated Rxon Skipping and Gene Editing. Intravascular Delivery of Naked DNA. Adenoviral-Mediated Gene Therapy. Retroviridae-based Gene Transfer Vectors. Gene Therapy Using Adeno-Associated Viral Vectors. Regional and Systemic Gene Delivery using Viral Vectors.

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