Molecular Biology of Diabetes

I. Autoimmunity and Genetics; Insulin Synthesis and Secretion

Inbunden, Engelska, 1994

1 637 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

These comprehensive yet concise collections of articles by world experts survey the latest findings on the molecular biology of diabetes and insulin action and synthesize a coherent understanding of the subject. Topics include the etiology of type I and type II diabetes, molecular and cellular aspects of insulin action, and the mechanism of the insulin-stimulated glucose uptake.

Produktinformation

Utgivningsdatum:1994-09-02
Mått:152 x 229 x 33 mm
Vikt:839 g
Format:Inbunden
Språk:Engelska
Antal sidor:404
Upplaga:1994
Förlag:Humana Press Inc.
ISBN:9780896032866

Utforska kategorier

Medicin: diabetes inom Medicin
Biologi inom Naturvetenskap och teknik

Recensioner i media

This is an essential book for a medical library to have, and it is a welcome addition to the library of investigators in the field. Specialists in diabetes will also find this book very useful. - Kevan Herold, MD for Doody's Health Science Book Review Journal

Innehållsförteckning

Molecular Mechanisms of Autoimmunity and Genetics of Diabetes.- 1. Molecular Targets of the Autoimmunity of Type I Diabetes.- 2. Murine Transgenic Models of IDDM.- 3. Pancreatic Islet Transplantation.- 4. Pathogenesis of Autoimmune Diabetes.- Molecular and Cellular Aspects of Insulin Synthesis and Secretion.- 5. Insulin Gene Structure and Regulation.- 6. Molecular Engineering of Glucose-Regulated Insulin Secretion.- 7. Glucokinase Gene Expression and Regulation.- 8. Fundamentals of Fuel Sensing and Intermediary Metabolism in Pancreatic A-and B-Cells.- 9. Glucose Toxicity and the Insulin Gene.- 10. Proinsulin-Processing Endopeptidases.- 11. GTP and Its Binding Proteins in the Regulation of Insulin Exocytosis.- 12. ?-Cell Receptors: Mechanisms of Signal Transduction.- 13. Molecular Biology of the Ion Channels in the Pancreatic ?-Cell.- 14. Molecular Biology of Gap Junction Proteins.- 15. The Gluco-Incretin Hormone Glucagon-Like Peptide-1 and Its ?-Cell Receptor.- 16. Islet Amyloid Polypeptide (IAPP) and Insulin Secretion.