Handbook of Proteases in Cancer

Dr. Sajal Chakraborti is associated with the Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India. He conducted postdoctoral research at The Johns Hopkins University School of Medicine, New York Medical College, The University of Utah, and the University of Florida. He has over 35 years of teaching and independent research experience in Biochemistry and Cell Biology. He has published more than 140 original research papers, 25 review articles, and edited 17 books.

• I. General Aspects1.1. Influence of Serine Proteases on Bone Morphogenetic Proteins: Insights for Advancing Treatment Paradigms in Breast CancerAnmol Kapoor, Chandi C. Mandal1.2. Proteases in Cancer TheranosticsDeepmala Karmakar, Sanghamitra Sengupta1.3. Structural aspects of proteases in cancer therapeutics: A perspectiveAnirban Nandy, Sima Biswas, Angshuman BagchiII. Proteases in Cancer Therapy2.1 Ubiquitin specific proteases: The role and potential in cancer immunotherapyBee Ling Tan1, Ayman El-Meghawry El-Kenawy2,3, Yin Sim Tor42.2. Proteasome, the recycle bin of the cancer cellAmy Dunne Miller1, Vasudha Tandon1, Nilabja Sikdar2, Sourav Banerjee12.3. The role of caspase 3 in post chemotherapy breast and colorectal cancer relapse and metastasis.Andreja Leskovac, Sandra Petrovic2.4. Role of Serine Proteases in Gastric Cancer: Inhibition and CureReena Kumari1,2, Kshetrimayum Birla Singh2, Amit Kumar Rai1, Sivakumar Vijayaraghavalu2*2.5. Serine protease inhibitors in breast cancer therapyAbinaya Elango, Arunkumar Radhakrishnan*2.6. Serine proteases in cancer: Mechanisms and treatment optionsMadhu Tanya Singh; Ammu V. V. V. Ravi Kiran; Garikapati Kusuma Kumari; Praveen T. Krishnamurthy*2.7. Survivin, a moonlighting caspase inhibitor and potential oncotherapeutic targetAbdul Basit Baba1, Rajakishore Mishra2, Siddavaram Nagini32.8. Ubiquitin-specific proteases for the treatment of breast cancerSuchetana Pal1, Subhasish Sarkar2, Rajlakshmi Laha2, Somasri Dam2.9. Microbial secretory proteases: a new insight in the field of cancer therapiesNanda Singh, Rima Tapader, Amit Pal2.10. The emerging role of the γ-secretase inhibitors in cancer managementAnuj Kumar Borah1, Chongtham Sovachandra Singh1, Babiangshisha Kharbuli1, Anupam Chatterjee2, Subhendu Chakrabarty3, Amlan Das12.11. Cathepsins in cancer therapy and precision medicineNamrata Singh1*, Aqsa Khan2, Asma Mohin Rojewale1, Shinjinee Sengupta22.12. The Emerging Role of Calpain 2 Protease as a Therapeutic Target inBreast CancerPraveen Kumar Chandra Sekar1, Jayakumar Subramaniyan2, Ramakrishnan Veerabathiran1*III. Epigenetic Tools and Stem Cell Therapy3.1. Calpains, miRNA and cancer: an overviewSajal Chakraborti1*, Mahasweta Ghosh1, Rajabrata Bhuyan2, Dibyapriya Roy Chowdhury1, Tapati Chakraborti1 3.2. The roles of ubiquitin-specific proteases (USPs) in cancer stem cell maintenance.Kuan Ping Anga2, Won Fen Wonga3, Chung Yeng Looi3.3. Modulatory Effects of Stem Cell Therapy on Cysteine Proteases and Matrix Metaloproteases in Breast CancerNour Y. S. Yassin, Noha A. Ahmed, Manal N. Abdel Azeem, Osama M. Ahmed3.4. Application of metalloproteases in cancer stem cell therapyUju Dorathy Iliemene1*, Paul T. Olonishuwa1, and Mubarak Labaran Liman2 3.5. Regulatory Mechanisms and Clinical Potential of Epigenetic Targeting in GliomaYetirajam Rajesh, Suvendu Nandi, Priya Ghosh, Mahitosh Mandal*3.6. Associations of proteases and long non-coding RNAs in cancerGaurav Kumar Bhagat1, Dipanjan Guha2, Angshuman Bagchi3.7. Stem cell-mediated interventions in cancers caused by proteasesFarheen Showkata2, Sabra Parveena2, Neetu Badesraa2, Mohmmad Saleem Dar1,2, Md Mehedi Hossaina2, Mir Owais Ayaz1,2, Mohd Jamal Dar1,23.8. Stem cell therapy in bone marrow cancerArjun K R, Girish Kanavi K, Sudipta Choudhury, Mythreyi R, Kanthesh M BasalingappaIV. Nanotechnology Based Therapies4.1. Protease-targeting nanoparticles for cancer therapy and imagingSandra Petrovic*, Andreja Leskovac4.2. Nanomedicine role in proteolytic landscape of breast cancerSobia Noreen1, Mehwish Ishtiaq1, Sara Hasan1,2, Shazia Akram Ghumman3, Samina Aslam44.3. Proteasome Inhibitors and Nano-Delivery Systems for Therapy of Glioblastoma MultiformeMekala Janaki Ramaiah1, Sahiti Chamarthy1, Janumala Mary Edna1, Katari Sukeerthi2, Nallapaty Srilakshmi2, Prasanna Srinivasan Ramalingam3, Sivakumar Armugam34.4. Emerging proteases for molecular imaging and therapy in cancerPresenjit1,2, Shubhra Chaturvedi1, Vishaka Chaudhary1,3, V.P. Singh4, Kaman Singh2, A.K. Mishra1*4.5. Novel nano technologies associated with Car-T cell therapy in breast cancerAvipsa Hazra1, Ragini Khanna2, Parthiban R3, Gopenath TS4,Kanthesh BM1*V. Bioinformatics and System Biology 5.1. System biology approach of protease Cathepsin K in glioblastoma multiformePrasanna Srinivasan Ramalingam1, Sivakumar Arumugam1, Purushothaman Balakrishnan2, Janaki Ramaiah Mekala5.2. Omics technologies for matrix metalloproteinases: MMPs as cancer biomarkersSherlin Rosita Arockiaraj1, Jay Shree Mathivanan1, Shivani Jambulingam1, Karnati Balaji2, Mahima Bhardwaj2, Pushparaj Annadurai3, Thomas Jebastin1, Abhinav Parashar4, Daniel A. Gideon5*5.3. Designing Novel Serine Protease Inhibitors against Potential Biomarkers specific to Lung Adenocarcinoma through Systems Biology and Structural Bioinformatics ApproachesAnamika Mishra1, Aniket Naha2*, Soundharya H1, Soumitra Nath3*, Nibu Varghese4, Soumya R S55.4. System biology and bioinformatics approaches in HTLV-1 protease targeting adult T-cell leukemia diseaseChandrabose Selvaraj1, Sanjeev Kumar Singh2, Devadasan Velmurugan5.5. Protease profiling in lung cancer using bioinformatics toolsProtease Profiling in Lung Cancer using Bioinformatics ToolsGowrav Baradwaj, Avipsa Hazra, Dhanu AS and Kanthesh M Basalingappa