Computational and Experimental Studies in Alzheimer's Disease

Kunal Bhattacharya is currently working as assistant professor in Pratiksha Institute of Pharmaceutical Sciences, Assam, India. His area of specialization includes Computer aided drug design, Bioinformatics and Analytical Chemistry. He obtained his M.Pharm in Pharmaceutical Chemistry from Nitte University, Mangalore, India. He is currently pursuing his PhD in pharmaceutical sciences in neurodegenerative diseases from The Assam Royal Global University, Assam, India. Atanu Bhattacharjee is currently working as a professor at School of Pharmacy, The Assam Royal Global University, Assam, India. He is considered as pioneer in the field of pharmacognosy and phytochemistry. Dr. Bhattacharjee achieved his Ph.D in Pharmaceutical Sciences in the areas of phytochemistry and neuro-pharmacology from Nitte University, Mangalore, India. He worked extensively on various in silico, in vitro and in vivo experiments to encounter neuro-degenerative disorders like Alzheimer’s disease with folklore medicine from the Indian diaspora and to determine safety profiles and standardize medicinal plants.

• Chapter 1: Alzheimer's Disease: Epidemiology, Neuropathology, and NeurochemistryRaushan Kumar Chaudhary, Uday Venkat Mateti, Pukar Khanal, Kala Bahadur Rawal, Praneetha Jain, Vishal S Patil, Amit Kumar Shrivastava and B M PatilChapter 2: Preclinical Approach: In vivo and In vitro Methods for Evaluation of Anti-Alzheimer's DrugsNilutpal Sharma Bora, Bhargab Jyoti Sahariah, Chanam Melody Devi and Banshongdor H. MawliehChapter 3: Computational Insights into the Applications of Plant-Based Therapies in Alzheimer's DiseaseDibyajyoti Das, Satyendra Deka, Biswajit Devanath, Aparoop Das, Nongmaithem Randhoni Chanu and Ramen KalitaChapter 4: Advances in Applying Computer-Aided Drug Design for Alzheimer’s DiseaseBiswajit Devanath, Satyendra Deka, Dibyajyoti Das, Hans Raj Bhat, Nongmaithem Randhoni Chanu and Kunal BhattacharyaChapter 5: Biomarkers Analysis for Alzheimer's DiseaseShraddha M. Jadhav and Karan KumarChapter 6: Mechanistic Aspects of Neurodegeneration in Alzheimer's Disease and the Role of PhytochemicalsTrideep Saikia, Tutumoni Kalita, Bhanu P Sahu, Prakash Rajak, Bhargab Deka and Alakesh BharaliChapter 7: Computational Modelling of BACE-1, AChE, and Phosphodiesterase Inhibitors as Anti-Alzheimer's AgentsVishal S Patil, Jagadeesh Dodakallanavar, Pukar Khanal, B M Patil, Raushan K Chaudhary, Amit Kumar Shrivastava, Nongmaithem Randhoni Chanu, Darasaguppe R. Harish and Uday Venkat MatetiChapter 8: Therapeutic Application of Natural Products in Alzheimer’s Disease Using Computational MethodsMuhammad Aqib Shabbir, Muhammad Naveed, Maleeha Manzoor, Hafiz Muhammad Hurraira, Noor-ul-Ain and Fatima ZaidiChapter 9: Analysis of Potential Alzheimer's Disease Inhibitors Based on Computational Modelling with Multiple TargetsAnkita Dubey, Vrishti M Thakur, Raja Chakraborty, G.N. Darwhekar, Rupesh Kushwah and Rakhi KhabiyaChapter 10: Virtual Screening: Pioneering the Future of Drug Discovery in Alzheimer's DiseaseN. Yellasubbaiah, B. Sivakumar and B. NagasudhaIndex