Cell Signaling

Interplay, Mechanisms, and Therapeutic Implications

Inbunden, Engelska, 2025

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Beskrivning

This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus–receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences.Key Features:Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and diseaseIntroduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathwaysFocuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behaviorExamines the molecular aspects of cell surface adhesion receptors, elucidating protein–protein interactions, signaling cascades, and enzyme–substrate interactionsDiscusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders

Produktinformation

Utgivningsdatum:2025-04-16
Mått:178 x 254 x 27 mm
Vikt:950 g
Format:Inbunden
Språk:Engelska
Antal sidor:412
Förlag:Taylor & Francis Ltd
ISBN:9781032707440

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Mer om författaren

Dr Adeeb Shehzad is currently Associate Professor at Biodiversity Unit, Research Center, Dhofar University, Oman and OIC of Lab of Biochemistry at Department of Biomedical Engineering and Sciences, SMME, NUST, Pakistan. He obtained his B.Pharmacy from the University of Peshawar, Pakistan in 2003. He completed his MS and Ph.D degree from Kyungpook National University, South Korea (2008–2014). He has published over 100 scientific publications and book chapters in refereed journals. Before joining NUST, Dr Adeeb has worked production pharmacist at Glaxo Smith Kline Pvt Ltd, Karachi, Pakistan and Medicraft Pharmaceutical Pvt Ltd, Peshawar, Pakistan from 2003-2007. His research interest is mainly oriented to the screening and development of plant isolated compounds as anticancer agents, as well as investigating the modulation of different signaling pathways in different types of cancers causing drug resistance and poor prognosis. Dr Adeeb is also interesting in development of kits for diagnosis and drug release patches with validation in animal models. Dr Adeeb is working as Editorial board member for several journals and has authored two books with international publishers. He received a number of national and international awards in academics and research.

Innehållsförteckning

1. Introduction to cell signalingIshtiaq Ali, Muhammad Junaid, Ahmad Tariq, Fazli Wahid, Muhammad Imran Khan2. Regulation of Cell Signaling CascadesHabab Ali Ahmad, Muhammad Ibrahim, Fazli Wahid, Muhammad Imran Khan3. Cellular Receptors and Cell SignalingMaleeha Azhar, Aroob Hasan Khan, Aroosa Younis Nadeem, Areej Fatima, Adeeb Shehzad4. Signal Transduction and Integral Membrane ProteinsZain Saeed, Zohra Jabeen, Sehrish Kakakhel, Saira Justin, Aneela Javed5. Antigen-Antibody Interaction in cell signalingSaman Noor, Anam Fatima, Iman Fatima, Gul Naz, Aneela Javed6. Immunological and Neuron SynapsesMuhammad Salman Khalid, Somia Mazhar, Adeeb Shehzad7. Rhinoviruses receptors and their interactionsAreej A. Sattar, Ariba Qaiser, Sobia Manzoor8. Role of ligand and voltage gated ion channels in cell signalingMaham Maharangaiz, Hira, sadaf Mumtaz, Rumeza hanif, Aneela Javed9. Hormones and Receptors Interaction in Cell SignalingTehmina Bibi, Shahar Bano, Eun Kyoung Seo, Salman Khan10. Signaling Networks in Development and DifferentiationAroosa Younis Nadeem, Areej Fatima, Maleeha Azhar, Adeeb Shehzad11. Cell Signaling and MetabolismSaadia Zahid*, Sanila Amber, Laila tul Qadar, Akasha Khurshid12. Inflammatory Signaling and Immune ResponseNaseem Zehra, Zia Uddin, Muhammad Imran Amir Zada, Muhammad Ikram13. Cell Signaling in CancerKhoula Sharif Mughal, Nabi Shah, Muhammad Naeem, Muhammad Ikram14. Cell signaling pathways in endocrine diseasesGauhar Rehman, Adil Sher15. Cell Signaling in Neurological DisordersMuhammad Ibrar Khan, Muhammad Junaid, Salman Khan16. Cell Signaling and DiagnosisAreej Fatima, Ammad Jamil, Maleeha Azhar, Aroosa Younis Nadeem, Adeeb Shehzad17. Signal Transduction and Targeted TherapiesAyesha Khan, Ayesha Riaz, Asima Saeed, Muhammad Imran Khan18. Role of cell signaling in drug developmentTaimoor Musharaf, Anoosha Ahmed, Muhammad Asim Siddique, Wajahat Sultan Abbasi, Saadia Andleeb