Dr. Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy) and Chairman of the Basic Sciences Department (Medical Program) at Sulaiman AlRajhi University. Before his current assignment, he served in several prestigious institutions in various parts of the world. He has also served as Principal Investigator (PI) and Co-PI on multiple National Institute of Health (NIH) funded stem cell research projects. He has been on the editorial boards and invited reviewer panels for several respected international journals. His research focuses on using, either alone or in combination, DNA, miRNAs, and stem cells as “drugs,” a topic that has gained popularity in regenerative medicine. He has extensively published on cellular and sub-cellular preconditioning of stem cells and using their conditioned media for cell-free therapy. He has published nearly 350 book chapters, abstracts, and research papers in various books and leading research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, and Antioxidant Redox Signaling. He has also given numerous presentations and edited ten books covering various facets of stem cells and their applications from drug to drug development.

• About the Editor. List of Contributors. Chapter 1 Extracellular Vesicles as in Dentistry from Laboratory to Clinic. Chapter 2 Extracellular Vesicles–Based Cell-Free Therapies in Cardiovascular Diseases. Chapter 3 Regenerative Therapy with Extracellular Vesicles in Acute and Chronic Kidney Injury. Chapter 4 Isolation and Characterization of IPSC EVs Preconditioned with Severe Critically Ill COVID-19 Patient’s Serum. Chapter 5 Therapeutic Efficacy of Mesenchymal Stem Cells and Their Derived Exosomes in Different Neurodegenerative Disorders: Current Status and Future Perspectives. Chapter 6 Applications and Implications of Mesenchymal Stem Cell-Derived Exosomes in Ophthalmology. Chapter 7 Future Management of Type 2 Diabetes and Its Complications by Mesenchymal Stem Cell−Derived Exosomes (MSC-Exos). Chapter 8 Liquid Biopsy Biomarkers for Personalized Management in Heart Failure. Chapter 9 Prospective Implications of Autologous Platelet-Rich Plasma in Tissue Engineering and Organ Rejuvenation. Chapter 10 Cell-Free and Cell-Based Therapy in Regenerative Medicine. Chapter 11 Mesenchymal Cell-Free and Cell-Based Therapy in Regenerative Medicine: A Crucial Exploration of Formulation, GMP Production, Regulatory Approval, and Market Access. Chapter 12 Unveiling Mesenchymal Stem Cells Secretome Potentials in Regenerative Medicine and Disease Therapeutics. Chapter 13 Engineering Therapeutic Mesenchymal Stem Cells Secretome for Bone Regeneration. Chapter 14 Cell-Free Scaffolding: A Tissue-Engineering Approach with the Potential to Revolutionize the Regeneration of Chondral Tissue. Chapter 15 The Secretome of Mesenchymal Stromal Cells in Treating Intracerebral Hemorrhage: Our Experience. Chapter 16 Stem Cell Secretome as Theranostics for Traumatic Brain Injury. Chapter 17 Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 18 Mesenchymal Stem Cell Secretomes for Cell-Free Therapy of the Broken Heart. Chapter 19 From 2D to 3D and Cellular to Cell-Free: Evolutions in Strategies for Regenerative Medicine. Chapter 20 Cell-Free and Cell-Based Approaches in Neurological Surgery. Chapter 21 A Clinical Overview of Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 22 Autologous versus Allogenic Mesenchymal Stem Cells in Heart Disease: Revisiting Preclinical and Clinical Trials. Chapter 23 Exosomes and Encapsulated ExomiRs in Breast Cancer: Theragnostic Applications and Clinical Implications. Chapter 24 The Potential of Mesenchymal Stem Cell−Derived Exosomes in Cell-Free Therapy for Myocardial Repair. Chapter 25 Theragnostic Applications of Exosomes in Alzheimer’s Disease. Index.

Dr. Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy) and Chairman of the Basic Sciences Department (Medical Program) at Sulaiman AlRajhi University. Before his current assignment, he served in several prestigious institutions in various parts of the world. He has also served as Principal Investigator (PI) and Co-PI on multiple National Institute of Health (NIH) funded stem cell research projects. He has been on the editorial boards and invited reviewer panels for several respected international journals. His research focuses on using, either alone or in combination, DNA, miRNAs, and stem cells as “drugs,” a topic that has gained popularity in regenerative medicine. He has extensively published on cellular and sub-cellular preconditioning of stem cells and using their conditioned media for cell-free therapy. He has published nearly 350 book chapters, abstracts, and research papers in various books and leading research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, and Antioxidant Redox Signaling. He has also given numerous presentations and edited ten books covering various facets of stem cells and their applications from drug to drug development.

• About the Editor. List of Contributors. Chapter 1 Extracellular Vesicles as in Dentistry from Laboratory to Clinic. Chapter 2 Extracellular Vesicles–Based Cell-Free Therapies in Cardiovascular Diseases. Chapter 3 Regenerative Therapy with Extracellular Vesicles in Acute and Chronic Kidney Injury. Chapter 4 Isolation and Characterization of IPSC EVs Preconditioned with Severe Critically Ill COVID-19 Patient’s Serum. Chapter 5 Therapeutic Efficacy of Mesenchymal Stem Cells and Their Derived Exosomes in Different Neurodegenerative Disorders: Current Status and Future Perspectives. Chapter 6 Applications and Implications of Mesenchymal Stem Cell-Derived Exosomes in Ophthalmology. Chapter 7 Future Management of Type 2 Diabetes and Its Complications by Mesenchymal Stem Cell−Derived Exosomes (MSC-Exos). Chapter 8 Liquid Biopsy Biomarkers for Personalized Management in Heart Failure. Chapter 9 Prospective Implications of Autologous Platelet-Rich Plasma in Tissue Engineering and Organ Rejuvenation. Chapter 10 Cell-Free and Cell-Based Therapy in Regenerative Medicine. Chapter 11 Mesenchymal Cell-Free and Cell-Based Therapy in Regenerative Medicine: A Crucial Exploration of Formulation, GMP Production, Regulatory Approval, and Market Access. Chapter 12 Unveiling Mesenchymal Stem Cells Secretome Potentials in Regenerative Medicine and Disease Therapeutics. Chapter 13 Engineering Therapeutic Mesenchymal Stem Cells Secretome for Bone Regeneration. Chapter 14 Cell-Free Scaffolding: A Tissue-Engineering Approach with the Potential to Revolutionize the Regeneration of Chondral Tissue. Chapter 15 The Secretome of Mesenchymal Stromal Cells in Treating Intracerebral Hemorrhage: Our Experience. Chapter 16 Stem Cell Secretome as Theranostics for Traumatic Brain Injury. Chapter 17 Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 18 Mesenchymal Stem Cell Secretomes for Cell-Free Therapy of the Broken Heart. Chapter 19 From 2D to 3D and Cellular to Cell-Free: Evolutions in Strategies for Regenerative Medicine. Chapter 20 Cell-Free and Cell-Based Approaches in Neurological Surgery. Chapter 21 A Clinical Overview of Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 22 Autologous versus Allogenic Mesenchymal Stem Cells in Heart Disease: Revisiting Preclinical and Clinical Trials. Chapter 23 Exosomes and Encapsulated ExomiRs in Breast Cancer: Theragnostic Applications and Clinical Implications. Chapter 24 The Potential of Mesenchymal Stem Cell−Derived Exosomes in Cell-Free Therapy for Myocardial Repair. Chapter 25 Theragnostic Applications of Exosomes in Alzheimer’s Disease. Index.

Dr. Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy) and Chairman of the Basic Sciences Department (Medical Program) at Sulaiman AlRajhi University. Before his current assignment, he served in several prestigious institutions in various parts of the world. He has also served as Principal Investigator (PI) and Co-PI on multiple National Institute of Health (NIH) funded stem cell research projects. He has been on the editorial boards and invited reviewer panels for several respected international journals. His research focuses on using, either alone or in combination, DNA, miRNAs, and stem cells as “drugs,” a topic that has gained popularity in regenerative medicine. He has extensively published on cellular and sub-cellular preconditioning of stem cells and using their conditioned media for cell-free therapy. He has published nearly 350 book chapters, abstracts, and research papers in various books and leading research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, and Antioxidant Redox Signaling. He has also given numerous presentations and edited ten books covering various facets of stem cells and their applications from drug to drug development.

• About the Editor. List of Contributors. Chapter 1 Extracellular Vesicles as in Dentistry from Laboratory to Clinic. Chapter 2 Extracellular Vesicles–Based Cell-Free Therapies in Cardiovascular Diseases. Chapter 3 Regenerative Therapy with Extracellular Vesicles in Acute and Chronic Kidney Injury. Chapter 4 Isolation and Characterization of IPSC EVs Preconditioned with Severe Critically Ill COVID-19 Patient’s Serum. Chapter 5 Therapeutic Efficacy of Mesenchymal Stem Cells and Their Derived Exosomes in Different Neurodegenerative Disorders: Current Status and Future Perspectives. Chapter 6 Applications and Implications of Mesenchymal Stem Cell-Derived Exosomes in Ophthalmology. Chapter 7 Future Management of Type 2 Diabetes and Its Complications by Mesenchymal Stem Cell−Derived Exosomes (MSC-Exos). Chapter 8 Liquid Biopsy Biomarkers for Personalized Management in Heart Failure. Chapter 9 Prospective Implications of Autologous Platelet-Rich Plasma in Tissue Engineering and Organ Rejuvenation. Chapter 10 Cell-Free and Cell-Based Therapy in Regenerative Medicine. Chapter 11 Mesenchymal Cell-Free and Cell-Based Therapy in Regenerative Medicine: A Crucial Exploration of Formulation, GMP Production, Regulatory Approval, and Market Access. Chapter 12 Unveiling Mesenchymal Stem Cells Secretome Potentials in Regenerative Medicine and Disease Therapeutics. Chapter 13 Engineering Therapeutic Mesenchymal Stem Cells Secretome for Bone Regeneration. Chapter 14 Cell-Free Scaffolding: A Tissue-Engineering Approach with the Potential to Revolutionize the Regeneration of Chondral Tissue. Chapter 15 The Secretome of Mesenchymal Stromal Cells in Treating Intracerebral Hemorrhage: Our Experience. Chapter 16 Stem Cell Secretome as Theranostics for Traumatic Brain Injury. Chapter 17 Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 18 Mesenchymal Stem Cell Secretomes for Cell-Free Therapy of the Broken Heart. Chapter 19 From 2D to 3D and Cellular to Cell-Free: Evolutions in Strategies for Regenerative Medicine. Chapter 20 Cell-Free and Cell-Based Approaches in Neurological Surgery. Chapter 21 A Clinical Overview of Cell-Free and Cell-Based Therapies in Regenerative Medicine. Chapter 22 Autologous versus Allogenic Mesenchymal Stem Cells in Heart Disease: Revisiting Preclinical and Clinical Trials. Chapter 23 Exosomes and Encapsulated ExomiRs in Breast Cancer: Theragnostic Applications and Clinical Implications. Chapter 24 The Potential of Mesenchymal Stem Cell−Derived Exosomes in Cell-Free Therapy for Myocardial Repair. Chapter 25 Theragnostic Applications of Exosomes in Alzheimer’s Disease. Index.