Peptide Libraries

Methods and Protocols

AvHans Michael Maric,Ronald Frank

Inbunden, Engelska, 2025

Del 2934 i serien Methods in Molecular Biology

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Beskrivning

This volume provides a collection of novel and emerging methods for the generation and application of peptide libraries.

Produktinformation

Utgivningsdatum:2025-07-16
Mått:178 x 254 x 23 mm
Vikt:799 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:306
Förlag:Springer-Verlag New York Inc.
ISBN:9781071645772

Utforska kategorier

Biokemi inom Naturvetenskap och teknik

Innehållsförteckning

My Perspective on OBOC Combinatorial Technology.- Encoded Peptide Library Synthesis and Applications, a Mini-Review.- Resemblance-Ranking Peptide Library as a Representation of a Complex Proteome.- β-Hairpin Peptidomimetics for Protein-Protein Interaction Inhibition.- Preparation of µSPOT Lactam-Cyclized Peptides for Ligand Optimization.- Construction of Cyclic Peptide-Libraries Immobilized on Gel-type Supports for Screening towards Discovery of Interacting Peptides.- Large Macrocyclic Libraries via Thioether Cyclization.- Protease Specificity Profiling using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry.- Parallel and Automated PNA Synthesis in µSPOT Format.- Late-Stage Functionalization of Peptides on Solid-Phase via Photochemical Decarboxylative Arylation.- Building Blocks for the Screening of Histone Deacetylase Inhibitors using µSPOT.- Parallel Synthesis of Glycopeptide Libraries using Glyco-SPOT Synthesis.- Facile High-Throughput Pre-Purification of Biological Samples for Library-Scale Peptide Interaction Studies.- Fmoc Solid-Phase FIT-PNA Synthesis – Manual and Automated Methodologies.- Guidelines for High-throughput Engineering of Non-Ribosomal Peptide Synthetase Libraries.- RIPP Enzymes for Biosynthetically Derived Cyclic Peptide Libraries.- Quantitative Affinity Screening of Macrocyclic Peptide Libraries using Yeast Surface Display Technology.- Ultra-High Throughput Screening of Cystine-Rich Peptide Libraries via Yeast Surface Display.- The Construction of dsDNA-Based AND-Gate (DBAG) Peptide Library in Mammalian Cells.