This fully updated volume focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with a multitude of practical applications. Examination of the application of sensors for enantiodifferentiation as well as chapters on the analysis of analyte-selector complexes by NMR spectroscopy and molecular modeling have been included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and practical, Chiral Separations: Methods and Protocols, Fourth Edition serves as a helpful guide for analytical chemists working on stereochemical problems in the fields of pharmacy, chemistry, biochemistry, food chemistry, molecular biology, forensics, environmental sciences, or cosmetics in academia, government, or industry.