Kenneth S. Kendler is a professor and eminent scholar at the Virginia Institute for Psychiatric and Behavioral Genetics and Virginia Commonwealth University. He is also a member of the National Academy of Medicine, where he is the recipient of many honors and awards. Josef Parnas is a clinical professor at the Department of Clinical Medicine and co-founder of the interdisciplinary theoretical institute The Center for Subjectivity Research at the University of Copenhagen. Peter Zachar is a professor in the Department of Psychology and the associate dean of the College of Sciences at Auburn University, Montgomery.

'The editors continue to deepen the analysis of the conceptual basis of psychopathological science through their astutely-framed, thematic book. They have assembled a diverse and expert group of contributors in considering the range of sciences relevant to psychopathology. This volume offers an outstanding pedagogy, including introductory overviews, and insightfully-chosen commentaries throughout.' John Z. Sadler, The Daniel W. Foster Professor of Medical Ethics and Distinguished Teaching Professor, University of Texas Southwestern Medical Center

• Introduction; Part I. Neuroscience, Mechanisms and RDoC: 1. Introduction Peter Zachar; 2. Rethinking psychiatric disorders in terms of heterarchical networks of control mechanisms William Bechtel; 3. A typology of levels of mechanisms involved in the etiology of psychiatric illness Kenneth S. Kendler; 4. Introduction Kenneth S. Kendler; 5. Wrangling the matrix: lessons from the RDoC working memory domain Robert M. Bilder; 6. Brain and mind in psychiatry? Presuppositions of cognitive ontology Georg Northoff; 7. Introduction Kenneth S. Kendler; 8. Tackling hard problems: neuroscience, treatment, and anxiety Daniel S. Pine; 9. Comments on Daniel S. Pine Kenneth F. Schaffner; Part II. Phenomenology, Biological Psychology, and the Mind-Body Problem: 10. Introduction Josef Parnas; 11. Body self-awareness: multiple levels or dynamical gestalt? Shaun Gallagher; 12. Commentary on Gallagher 'Body self-awareness: multiple levels or dynamical gestalt?' Jan-Willem Romeijn; 13. Introduction Josef Parnas; 14. Can psychiatry dispense with appeal to mental causation? John Campbell; 15. Folk psychology and Jaspers' empathic understanding: a conceptual exercise? Peter Zachar; 16. Introduction Peter Zachar; 17. Phenomenology of a disordered self in schizophrenia: example of an integrative level for psychiatric research Josef Parnas and Maja Zanderson; 18. Who is the psychiatric subject? Shaun Gallagher; 19. Introduction Kenneth S. Kendler; 20. Challenges in the relationships between psychological and biological phenomena in psychopathology Gregory A. Miller and Morgan E. Bartholomew; 21. Non-reductionism, eliminativism, and modularity in RDoC: thoughts about a progressive mechanistic science Peter Zachar; Part III. Taxonomy, Integration and Multiple Levels of Explanation: 22. Introduction Josef Parnas; 23. Descriptive psychopathology: a manifest level of analysis, or not? Peter Zachar; 24. Psychiatry without description Josef Parnas; 25. Introduction Peter Zachar; 26. Should psychiatry be precise? Reduction, big data, and nosological revision in mental health research Kathryn Tabb; 27. Commentary on should psychiatry be precise? Reduction, big data, and nosological revision in mental health research Robert M. Bilder; 28. Introduction Peter Zachar; 29. Psychiatric classification: an a-reductionist perspective Jan-Willem Romeijn and Hanna van Loo; 30. Double black diamond Eric Turkheimer; 31. Introduction Peter Zachar; 32. Approaches to multi-level models of fear: the what, where, why, how, and how much? Kenneth F. Schaffner; 33. Schaffner on levels and selves William Bechtel; 34. Introduction Kenneth S. Kendler; 35. Levels: what are they and what are they good for? James Woodward; 36. Levels of analysis in Alzheimer's disease research Stephan Heckers; 37. Introduction Peter Zachar; 38. The impact of faculty psychology and theories of psychological causation on the origins of modern psychiatric nosology Kenneth S. Kendler; 39. Commentary on 'The impact of faculty psychology and theories of psychological causation on the origins of modern psychiatric nosology' Gregory A. Miller; 40. Introduction Kenneth S. Kendler; 41. Psychiatric discourse: scientific reductionism for the autonomous person Stephan Heckers; 42. Comment on Stephan Heckers, 'Psychiatric discourse: scientific reductionism for the autonomous person' John Campbell; 43. Introduction Josef Parnas; 44. Entity focus: applied genetic science at different levels Eric Turkheimer; 45. Comment on 'Entity focus: applied genetic science at different levels' by Eric Turkheimer Kathryn Tabb.

Kenneth S. Kendler is a professor and eminent scholar at the Virginia Institute for Psychiatric and Behavioral Genetics and Virginia Commonwealth University. He is also a member of the National Academy of Medicine, where he is the recipient of many honors and awards. Josef Parnas is a clinical professor at the Department of Clinical Medicine and co-founder of the interdisciplinary theoretical institute The Center for Subjectivity Research at the University of Copenhagen. Peter Zachar is a professor in the Department of Psychology and the associate dean of the College of Sciences at Auburn University, Montgomery.

'The editors continue to deepen the analysis of the conceptual basis of psychopathological science through their astutely-framed, thematic book. They have assembled a diverse and expert group of contributors in considering the range of sciences relevant to psychopathology. This volume offers an outstanding pedagogy, including introductory overviews, and insightfully-chosen commentaries throughout.' John Z. Sadler, The Daniel W. Foster Professor of Medical Ethics and Distinguished Teaching Professor, University of Texas Southwestern Medical Center

• Introduction; Part I. Neuroscience, Mechanisms and RDoC: 1. Introduction Peter Zachar; 2. Rethinking psychiatric disorders in terms of heterarchical networks of control mechanisms William Bechtel; 3. A typology of levels of mechanisms involved in the etiology of psychiatric illness Kenneth S. Kendler; 4. Introduction Kenneth S. Kendler; 5. Wrangling the matrix: lessons from the RDoC working memory domain Robert M. Bilder; 6. Brain and mind in psychiatry? Presuppositions of cognitive ontology Georg Northoff; 7. Introduction Kenneth S. Kendler; 8. Tackling hard problems: neuroscience, treatment, and anxiety Daniel S. Pine; 9. Comments on Daniel S. Pine Kenneth F. Schaffner; Part II. Phenomenology, Biological Psychology, and the Mind-Body Problem: 10. Introduction Josef Parnas; 11. Body self-awareness: multiple levels or dynamical gestalt? Shaun Gallagher; 12. Commentary on Gallagher 'Body self-awareness: multiple levels or dynamical gestalt?' Jan-Willem Romeijn; 13. Introduction Josef Parnas; 14. Can psychiatry dispense with appeal to mental causation? John Campbell; 15. Folk psychology and Jaspers' empathic understanding: a conceptual exercise? Peter Zachar; 16. Introduction Peter Zachar; 17. Phenomenology of a disordered self in schizophrenia: example of an integrative level for psychiatric research Josef Parnas and Maja Zanderson; 18. Who is the psychiatric subject? Shaun Gallagher; 19. Introduction Kenneth S. Kendler; 20. Challenges in the relationships between psychological and biological phenomena in psychopathology Gregory A. Miller and Morgan E. Bartholomew; 21. Non-reductionism, eliminativism, and modularity in RDoC: thoughts about a progressive mechanistic science Peter Zachar; Part III. Taxonomy, Integration and Multiple Levels of Explanation: 22. Introduction Josef Parnas; 23. Descriptive psychopathology: a manifest level of analysis, or not? Peter Zachar; 24. Psychiatry without description Josef Parnas; 25. Introduction Peter Zachar; 26. Should psychiatry be precise? Reduction, big data, and nosological revision in mental health research Kathryn Tabb; 27. Commentary on should psychiatry be precise? Reduction, big data, and nosological revision in mental health research Robert M. Bilder; 28. Introduction Peter Zachar; 29. Psychiatric classification: an a-reductionist perspective Jan-Willem Romeijn and Hanna van Loo; 30. Double black diamond Eric Turkheimer; 31. Introduction Peter Zachar; 32. Approaches to multi-level models of fear: the what, where, why, how, and how much? Kenneth F. Schaffner; 33. Schaffner on levels and selves William Bechtel; 34. Introduction Kenneth S. Kendler; 35. Levels: what are they and what are they good for? James Woodward; 36. Levels of analysis in Alzheimer's disease research Stephan Heckers; 37. Introduction Peter Zachar; 38. The impact of faculty psychology and theories of psychological causation on the origins of modern psychiatric nosology Kenneth S. Kendler; 39. Commentary on 'The impact of faculty psychology and theories of psychological causation on the origins of modern psychiatric nosology' Gregory A. Miller; 40. Introduction Kenneth S. Kendler; 41. Psychiatric discourse: scientific reductionism for the autonomous person Stephan Heckers; 42. Comment on Stephan Heckers, 'Psychiatric discourse: scientific reductionism for the autonomous person' John Campbell; 43. Introduction Josef Parnas; 44. Entity focus: applied genetic science at different levels Eric Turkheimer; 45. Comment on 'Entity focus: applied genetic science at different levels' by Eric Turkheimer Kathryn Tabb.