Rajesh Kumar Dhanaraj, PhD, is a Full Professor at Symbiosis International (Deemed University), Pune, India. Balamurugan Balusamy, PhD, is an Associate Dean Student in Shiv Nadar University, Delhi-NCR. Prithi Samuel, PhD, is an Assistant Professor in the Department of Computational Intelligence at SRM Institute of Science and Technology, Kattankulathur Campus, Chennai. Ali Kashif Bashir, PhD, is a Chair Professor of Networks and Security at the Manchester Metropolitan University, UK. Seifedine Kadry, PhD, is a Full Professor of Data Science with the Department of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon; Department of Applied Data Science, Noroff University College, Kristiansand, Norway.

• About the Editors xxiiiList of Contributors xxvii1 Journey to Digital Twin Technology in Industrial Production: Evolution, Challenges, and Trends 1Prithi Samuel, Rajesh Kumar Dhanaraj, Balamurugan Balusamy, Ali Kashif Bashir, and Seifedine Kadry2 The State-of-the-Art Digital Twin Components in Industrial IoT Production: Theoretical and Practical Applications 23Kariyappa Janani, Sriramulu Ramamoorthy, Ramamoorthy Poorvadevi, and R. Gopal3 Decision Support System for Digital Twin-based Smart Manufacturing Systems and Design in Industry 5.0 59B. Akoramurthy, B. Surendiran, K. Dhivya, Subrata Chowdhury, Ramya Govindaraj, and Gautam Srivastava4 Industrial Internet of Things: Enhancement of Industries with Hyperautomation for Smart Manufacturing Machines 85G.S. Gopika, M. Sree Krishna, R.S. Rajasree, S. Gnanavel, and Achyut Shankar5 Digital Twins Model of Industrial Production Control Management Using Deep Learning Techniques 103Govindaraj Venkatesan, Rajendra Narasimman Karthika, and Ali Kashif Bashir6 Digital Twin for Sustainable Development of Intelligent Manufacturing 125Kuldeep Singh Kaswan, Jagjit Singh Dhatterwal, Sumit Singh Dhanda, Balamurugan Balusamy, and Azween Abdullah7 Digital Twins in Flexible Industrial Production and Smart Manufacturing: Case Study on Intelligent Logistics and Supply Chain Management 161S. Jeyalakshmi, A. Prasanth, M. Yogeshwari, and Ahmed A. Elngar8 Applications and Use Cases of Digital Twins in Industry: 3D Graphics, Visualization, Modeling, Printing, and Reality Platforms 173Suganthi Selvakumar, Saranya Jayaraman, Selvakumar Varadarajan Subramani, Sheena Christabel Pravin, Gayathri Radhakrishnan, and Ponmurugan Karuppiah9 Cobots in Smart Manufacturing and Production for Industry 5.0 201Jeyalakshmi Jeyabalan, Eugene Berna, Prithi Samuel, and Vikneswaran Vijean10 Edge Computing and Artificial Intelligence-Based Internet of Things for Industry 5.0: Framework, Challenges, Use Cases, and Research Directions 221Ramya Ramanathan, Sriramulu Ramamoorthy, and Simon Grima11 Smart Manufacturing with a Digital Twin–Driven Cyber-physical System: Case Study and Application Scenario 247P. Abinaya, S. Prem Kumar, P. Sivaprakash, K. Arun Kumar, B. Shuriya, and Surbhi Bhatia Khan12 Industrial Excellence Through Virtual Factory Simulation and Digital Modeling Innovations for Next-Generation Manufacturing System Design 277Pravin Satyanarayan Metkewar13 Digital Transformation in the Pharmaceutical and Biotech Industry: Challenges and Research Directions 297S. Subha, M. Shanmugathai, A. Prasanth, S. Sree Varagi, and V. Dhanashree14 Overcoming the Obstacles of Motion Sickness in the Metaverse’s Digital Twins 325Erik Geslin and Diego Saldivar15 Smart Cities Using Digital Twins and Industrial IoT Based Technologies: Tools and Products from the Industry Sector 353Aravinda Koithyar, Asha Venkataramana, Balasubramanian Prabhu Kavin, and Gan Hong Seng16 Digital Twin in Aerospace Industry and Aerospace Transformation Through Industry 4.0 Technologies 381Vijay Kandasamy, Eashaan Manohar, Saiganesh Bhaskar, and Ganeshkumar PerumalIndex 405

Rajesh Kumar Dhanaraj, PhD, is a Full Professor at Symbiosis International (Deemed University), Pune, India. Balamurugan Balusamy, PhD, is an Associate Dean Student in Shiv Nadar University, Delhi-NCR. Prithi Samuel, PhD, is an Assistant Professor in the Department of Computational Intelligence at SRM Institute of Science and Technology, Kattankulathur Campus, Chennai. Ali Kashif Bashir, PhD, is a Chair Professor of Networks and Security at the Manchester Metropolitan University, UK. Seifedine Kadry, PhD, is a Full Professor of Data Science with the Department of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon; Department of Applied Data Science, Noroff University College, Kristiansand, Norway.

• About the Editors xxiiiList of Contributors xxvii1 Journey to Digital Twin Technology in Industrial Production: Evolution, Challenges, and Trends 1Prithi Samuel, Rajesh Kumar Dhanaraj, Balamurugan Balusamy, Ali Kashif Bashir, and Seifedine Kadry2 The State-of-the-Art Digital Twin Components in Industrial IoT Production: Theoretical and Practical Applications 23Kariyappa Janani, Sriramulu Ramamoorthy, Ramamoorthy Poorvadevi, and R. Gopal3 Decision Support System for Digital Twin-based Smart Manufacturing Systems and Design in Industry 5.0 59B. Akoramurthy, B. Surendiran, K. Dhivya, Subrata Chowdhury, Ramya Govindaraj, and Gautam Srivastava4 Industrial Internet of Things: Enhancement of Industries with Hyperautomation for Smart Manufacturing Machines 85G.S. Gopika, M. Sree Krishna, R.S. Rajasree, S. Gnanavel, and Achyut Shankar5 Digital Twins Model of Industrial Production Control Management Using Deep Learning Techniques 103Govindaraj Venkatesan, Rajendra Narasimman Karthika, and Ali Kashif Bashir6 Digital Twin for Sustainable Development of Intelligent Manufacturing 125Kuldeep Singh Kaswan, Jagjit Singh Dhatterwal, Sumit Singh Dhanda, Balamurugan Balusamy, and Azween Abdullah7 Digital Twins in Flexible Industrial Production and Smart Manufacturing: Case Study on Intelligent Logistics and Supply Chain Management 161S. Jeyalakshmi, A. Prasanth, M. Yogeshwari, and Ahmed A. Elngar8 Applications and Use Cases of Digital Twins in Industry: 3D Graphics, Visualization, Modeling, Printing, and Reality Platforms 173Suganthi Selvakumar, Saranya Jayaraman, Selvakumar Varadarajan Subramani, Sheena Christabel Pravin, Gayathri Radhakrishnan, and Ponmurugan Karuppiah9 Cobots in Smart Manufacturing and Production for Industry 5.0 201Jeyalakshmi Jeyabalan, Eugene Berna, Prithi Samuel, and Vikneswaran Vijean10 Edge Computing and Artificial Intelligence-Based Internet of Things for Industry 5.0: Framework, Challenges, Use Cases, and Research Directions 221Ramya Ramanathan, Sriramulu Ramamoorthy, and Simon Grima11 Smart Manufacturing with a Digital Twin–Driven Cyber-physical System: Case Study and Application Scenario 247P. Abinaya, S. Prem Kumar, P. Sivaprakash, K. Arun Kumar, B. Shuriya, and Surbhi Bhatia Khan12 Industrial Excellence Through Virtual Factory Simulation and Digital Modeling Innovations for Next-Generation Manufacturing System Design 277Pravin Satyanarayan Metkewar13 Digital Transformation in the Pharmaceutical and Biotech Industry: Challenges and Research Directions 297S. Subha, M. Shanmugathai, A. Prasanth, S. Sree Varagi, and V. Dhanashree14 Overcoming the Obstacles of Motion Sickness in the Metaverse’s Digital Twins 325Erik Geslin and Diego Saldivar15 Smart Cities Using Digital Twins and Industrial IoT Based Technologies: Tools and Products from the Industry Sector 353Aravinda Koithyar, Asha Venkataramana, Balasubramanian Prabhu Kavin, and Gan Hong Seng16 Digital Twin in Aerospace Industry and Aerospace Transformation Through Industry 4.0 Technologies 381Vijay Kandasamy, Eashaan Manohar, Saiganesh Bhaskar, and Ganeshkumar PerumalIndex 405

Rajesh Kumar Dhanaraj, PhD, is a Full Professor at Symbiosis International (Deemed University), Pune, India. Balamurugan Balusamy, PhD, is an Associate Dean Student in Shiv Nadar University, Delhi-NCR. Prithi Samuel, PhD, is an Assistant Professor in the Department of Computational Intelligence at SRM Institute of Science and Technology, Kattankulathur Campus, Chennai. Ali Kashif Bashir, PhD, is a Chair Professor of Networks and Security at the Manchester Metropolitan University, UK. Seifedine Kadry, PhD, is a Full Professor of Data Science with the Department of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon; Department of Applied Data Science, Noroff University College, Kristiansand, Norway.

• About the Editors xxiiiList of Contributors xxvii1 Journey to Digital Twin Technology in Industrial Production: Evolution, Challenges, and Trends 1Prithi Samuel, Rajesh Kumar Dhanaraj, Balamurugan Balusamy, Ali Kashif Bashir, and Seifedine Kadry2 The State-of-the-Art Digital Twin Components in Industrial IoT Production: Theoretical and Practical Applications 23Kariyappa Janani, Sriramulu Ramamoorthy, Ramamoorthy Poorvadevi, and R. Gopal3 Decision Support System for Digital Twin-based Smart Manufacturing Systems and Design in Industry 5.0 59B. Akoramurthy, B. Surendiran, K. Dhivya, Subrata Chowdhury, Ramya Govindaraj, and Gautam Srivastava4 Industrial Internet of Things: Enhancement of Industries with Hyperautomation for Smart Manufacturing Machines 85G.S. Gopika, M. Sree Krishna, R.S. Rajasree, S. Gnanavel, and Achyut Shankar5 Digital Twins Model of Industrial Production Control Management Using Deep Learning Techniques 103Govindaraj Venkatesan, Rajendra Narasimman Karthika, and Ali Kashif Bashir6 Digital Twin for Sustainable Development of Intelligent Manufacturing 125Kuldeep Singh Kaswan, Jagjit Singh Dhatterwal, Sumit Singh Dhanda, Balamurugan Balusamy, and Azween Abdullah7 Digital Twins in Flexible Industrial Production and Smart Manufacturing: Case Study on Intelligent Logistics and Supply Chain Management 161S. Jeyalakshmi, A. Prasanth, M. Yogeshwari, and Ahmed A. Elngar8 Applications and Use Cases of Digital Twins in Industry: 3D Graphics, Visualization, Modeling, Printing, and Reality Platforms 173Suganthi Selvakumar, Saranya Jayaraman, Selvakumar Varadarajan Subramani, Sheena Christabel Pravin, Gayathri Radhakrishnan, and Ponmurugan Karuppiah9 Cobots in Smart Manufacturing and Production for Industry 5.0 201Jeyalakshmi Jeyabalan, Eugene Berna, Prithi Samuel, and Vikneswaran Vijean10 Edge Computing and Artificial Intelligence-Based Internet of Things for Industry 5.0: Framework, Challenges, Use Cases, and Research Directions 221Ramya Ramanathan, Sriramulu Ramamoorthy, and Simon Grima11 Smart Manufacturing with a Digital Twin–Driven Cyber-physical System: Case Study and Application Scenario 247P. Abinaya, S. Prem Kumar, P. Sivaprakash, K. Arun Kumar, B. Shuriya, and Surbhi Bhatia Khan12 Industrial Excellence Through Virtual Factory Simulation and Digital Modeling Innovations for Next-Generation Manufacturing System Design 277Pravin Satyanarayan Metkewar13 Digital Transformation in the Pharmaceutical and Biotech Industry: Challenges and Research Directions 297S. Subha, M. Shanmugathai, A. Prasanth, S. Sree Varagi, and V. Dhanashree14 Overcoming the Obstacles of Motion Sickness in the Metaverse’s Digital Twins 325Erik Geslin and Diego Saldivar15 Smart Cities Using Digital Twins and Industrial IoT Based Technologies: Tools and Products from the Industry Sector 353Aravinda Koithyar, Asha Venkataramana, Balasubramanian Prabhu Kavin, and Gan Hong Seng16 Digital Twin in Aerospace Industry and Aerospace Transformation Through Industry 4.0 Technologies 381Vijay Kandasamy, Eashaan Manohar, Saiganesh Bhaskar, and Ganeshkumar PerumalIndex 405