Barbara J. Bain is an Australian haematologist. She is Professor of Diagnostic Haematology at the Imperial College London Faculty of Medicine and a consultant at St Mary’s Hospital, London. She is known as the author of reference textbooks in the field of haematology that form the core curriculum for laboratory morphology and pathology. She recently received an AM in the 2020 Queen’s Birthday Honours and in 2018 a European Haematology Association Mentoring and Teaching Award. Mike Leach is a haematologist with an interest in diagnostic haematopathology. He is a Consultant at the Beatson West of Scotland Cancer Centre and Gartnavel Laboratory in Glasgow, UK. He is known for a series of textbooks in this field with a focus on haematology diagnosis and the application of flow cytometry.

• Preface viiAcknowledgements ixCommonly Used Abbreviations xi1 The Nature of Leukaemia, Cytology, Cytochemistry and the Morphological Classification of Acute Leukaemia 12 Immunophenotyping and Cytogenetic/Molecular Genetic Analyis 753 Acute Myeloid Leukaemia: Integration of Morphological, Immunophenotypic and Genetic Information: the WHO and International Consensus Classifications 1414 Acute Lymphoblastic Leukaemia and Acute Leukaemia of Mixed or Ambiguous Lineage 2715 The Myelodysplastic Syndromes, the Myelodysplastic/Myeloproliferative Neoplasms and Juvenile Myelomonocytic Leukaemia 3276 Chronic Myeloid Leukaemias 4117 Lymphoid Leukaemias of Mature B, T and Natural Killer Cells 4698 Leukaemia Diagnosis in Resource- Poor Countries 593Index 607

Barbara J. Bain is an Australian haematologist. She is Professor of Diagnostic Haematology at the Imperial College London Faculty of Medicine and a consultant at St Mary’s Hospital, London. She is known as the author of reference textbooks in the field of haematology that form the core curriculum for laboratory morphology and pathology. She recently received an AM in the 2020 Queen’s Birthday Honours and in 2018 a European Haematology Association Mentoring and Teaching Award. Mike Leach is a haematologist with an interest in diagnostic haematopathology. He is a Consultant at the Beatson West of Scotland Cancer Centre and Gartnavel Laboratory in Glasgow, UK. He is known for a series of textbooks in this field with a focus on haematology diagnosis and the application of flow cytometry.

• Preface viiAcknowledgements ixCommonly Used Abbreviations xi1 The Nature of Leukaemia, Cytology, Cytochemistry and the Morphological Classification of Acute Leukaemia 12 Immunophenotyping and Cytogenetic/Molecular Genetic Analyis 753 Acute Myeloid Leukaemia: Integration of Morphological, Immunophenotypic and Genetic Information: the WHO and International Consensus Classifications 1414 Acute Lymphoblastic Leukaemia and Acute Leukaemia of Mixed or Ambiguous Lineage 2715 The Myelodysplastic Syndromes, the Myelodysplastic/Myeloproliferative Neoplasms and Juvenile Myelomonocytic Leukaemia 3276 Chronic Myeloid Leukaemias 4117 Lymphoid Leukaemias of Mature B, T and Natural Killer Cells 4698 Leukaemia Diagnosis in Resource- Poor Countries 593Index 607

Barbara J. Bain is an Australian haematologist. She is Professor of Diagnostic Haematology at the Imperial College London Faculty of Medicine and a consultant at St Mary’s Hospital, London. She is known as the author of reference textbooks in the field of haematology that form the core curriculum for laboratory morphology and pathology. She recently received an AM in the 2020 Queen’s Birthday Honours and in 2018 a European Haematology Association Mentoring and Teaching Award. Mike Leach is a haematologist with an interest in diagnostic haematopathology. He is a Consultant at the Beatson West of Scotland Cancer Centre and Gartnavel Laboratory in Glasgow, UK. He is known for a series of textbooks in this field with a focus on haematology diagnosis and the application of flow cytometry.

• Preface viiAcknowledgements ixCommonly Used Abbreviations xi1 The Nature of Leukaemia, Cytology, Cytochemistry and the Morphological Classification of Acute Leukaemia 12 Immunophenotyping and Cytogenetic/Molecular Genetic Analyis 753 Acute Myeloid Leukaemia: Integration of Morphological, Immunophenotypic and Genetic Information: the WHO and International Consensus Classifications 1414 Acute Lymphoblastic Leukaemia and Acute Leukaemia of Mixed or Ambiguous Lineage 2715 The Myelodysplastic Syndromes, the Myelodysplastic/Myeloproliferative Neoplasms and Juvenile Myelomonocytic Leukaemia 3276 Chronic Myeloid Leukaemias 4117 Lymphoid Leukaemias of Mature B, T and Natural Killer Cells 4698 Leukaemia Diagnosis in Resource- Poor Countries 593Index 607