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    1. Medicin
    2. Klinisk medicin och internmedicin
    3. Dermatologi

    Stem Cell Therapy in Dermatological Disorders

    AvSumel Ashique,Sanjay Dey

    Inbunden, Engelska, 2025

    2 460 kr

    Beställningsvara. Skickas inom 5-8 vardagar. Fri frakt över 249 kr.

    Beskrivning

    This book provides a comprehensive understanding of the transformative potential of stem cell therapies for improving skin health and treating debilitating dermatological disorders. Stem Cell Therapy in Dermatological Disorders delves into the emerging field of stem cell therapy as a revolutionary approach to treating various dermatological conditions. This book provides a comprehensive overview of the science behind stem cell technology, focusing on its applications in skin regeneration, wound healing, and the management of chronic skin diseases. It examines the cellular and molecular mechanisms that make stem cells uniquely suited for dermatological use, exploring their ability to promote tissue repair, modulate inflammation, and restore the skin’s structural integrity. This book aims to bridge the gap between experimental research and clinical application, presenting up-to-date findings on the different types of stem cells used in dermatology, including mesenchymal stem cells, induced pluripotent stem cells, and embryonic stem cells. It highlights the role of stem cells in addressing disorders such as atopic dermatitis, psoriasis, vitiligo, and chronic non-healing wounds. Readers will find in-depth discussions on current therapeutic techniques, the challenges of translating preclinical studies to human trials, and the ethical considerations associated with stem cell therapies. In addition to discussing the state-of-the-art in stem cell-based treatments, the book also casts an eye on the future, identifying gaps in existing knowledge and potential areas for innovation. The authors provide insights into novel delivery systems, genetic engineering advancements, and combinatory approaches that may enhance the efficacy and safety of stem cell therapies in dermatology. This volume serves as an essential resource for dermatologists, researchers, and clinicians seeking to understand the transformative potential of stem cell therapies in improving skin health and treating debilitating dermatological disorders. Readers will find the book: Explores the latest breakthroughs in stem cell therapy for skin disorders;Bridges the gap between basic science and clinical applications;Discusses mesenchymal stem cells (MSCs), iPSCs, and exosome-based therapies.Audience Dermatologists, dermatopathologists, plastic surgeons, medical aestheticians, researchers, clinicians, and biotechnology and pharmaceutical professionals involved in regenerative medicine and aesthetic dermatology.

    Produktinformation

    • Utgivningsdatum:2025-09-30
    • Vikt:771 g
    • Format:Inbunden
    • Språk:Engelska
    • Antal sidor:400
    • Förlag:John Wiley & Sons Inc
    • ISBN:9781394393114

    Utforska kategorier

    • Dermatologi inom Medicin
    • Cellbiologi inom Naturvetenskap och teknik

    Mer om författaren

    Sumel Ashique is an assistant professor at Bharat Technology, India with four years of teaching experience. He has published over 80 articles in national and international journals, 20 book chapters, 14 books, and five patents. His research focuses on drug delivery, nanotechnology, and targeted treatment strategies. Sanjay Dey, PhD is a professor in the Department of Pharmaceutical Technology in the School of Health and Medical Sciences at Adamas University, India with over 15 years of experience. He has published 31 research articles and 11 review articles in national and international journals, eight book chapters, and five patents. His research interests include the development of conventional drug delivery systems and novel drug delivery systems. Biplab Debnath, PhD is a distinguished principal and professor at Bharat Technology, India. He has published over 60 research and review papers in international journals, five book chapters, eight books, and two granted patents. His research expertise lies in silico synthesis and the biological activities of novel heterocyclic molecules. Mohhammad Ramzan, PhD of the School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India, has over ten years of teaching and research experience. He has over 36 publications in reputed national and international journals, four book chapters, and five copyrights. His research focuses on nanoparticulates and vesicular drug delivery systems. Swarupananda Mukherjee, PhD is an associate professor and Head of the Department, Pharmaceutics Department, NSHM Knowledge Campus, Kolkata, College of Pharmaceutical Technology, Kolkata, India and has over 18 years of teaching and research experience. He has over 85 publications in reputed national and international journals, 20 books, and 15 patents. His research focuses on nanoparticulate drug delivery systems.

    Innehållsförteckning

    • Preface xv1 Fundamentals of Stem Cell Therapy in Disease Prevention 1Rajarshi Nath, Arijit Das, Shambo Panda, Souvik Biswas and Biplab Debnath1.1 Introduction to Stem Cell Therapy 21.2 Mechanisms of Stem Cell Therapy 41.3 Applications of Stem Cell Therapy in Disease Prevention 81.4 Challenges and Limitations of Stem Cell Therapy 111.5 Future Perspectives and Innovations 142 Stem Cell Therapy on Skin: Mechanisms and Recent Advances 19Koushik Jana, Md. Kabirul Islam Mollah, Gouranga Dutta, Goutam Ghosh and Goutam Rath2.1 Background and Historical Overview of Stem Cell Therapy 202.2 Skin Diseases and Stem Cell Treatment 212.3 Types of Stem Cells and Their Mechanism in Skin Diseases 272.4 Recent Advancements in Skin Disease Stem Cell Therapy 302.5 Challenges and Regulatory Aspects 342.6 Conclusion and Future Outlooks 343 Stem Cell Therapy: Significant Option for Psoriasis Management 43Joy Das, Utpal Bhui, Saistha Anjum, Sumel Ashique, Mohammad Muztaba and Sanjay Dey3.1 Introduction 443.2 Advantages of Stem Cell Therapy for Psoriasis 463.3 Types of Stem Cell Therapy in Psoriasis 483.4 Therapeutic Value of Stem Cell 513.5 Challenges in Cost, Availability, and Clinical Application 603.6 Regulatory Aspects of Stem Cell Therapy 643.7 Conclusion and Future Directions 654 Therapeutic Modalities of Stem Cells: Skin Cancer Treatment 79Dipanjan Karati, Soumi Das and Swarupananda Mukherjee4.1 Introduction 804.2 Stem Cells in Skin Cancer: A Brief Overview 814.3 Therapeutic Modalities of Stem Cells in Skin Cancer Treatment 834.4 Emerging Trends and Advanced Technologies in Stem Cell Therapy for Skin Cancer 904.5 Challenges and Limitations of Stem Cell–Based Therapies 954.6 Preclinical and Clinical Studies: Insights and Outcomes 964.7 Future Directions and Perspectives 974.8 Conclusion 985 Therapeutic Advancement of Stem Cell Therapy in Atopic Dermatitis 109Kishanta Kumar Pradhan, Rojalin Samanta, Reechik Bandyopadhyay, Arnab Seth and Chowdhury Mobaswar Hossain5.1 Background of Atopic Dermatitis 1105.2 Stem Cell Biology and Mechanisms 1115.3 Types and Pathophysiology of AD 1205.4 Different Stem Cell Application on AD 1225.5 Challenges and Ethical Considerations 1255.6 Recent Advancement of Stem Cell Therapy on AD 1285.7 Clinical Research Updates 1306 Stem Cell Therapy: A Significant Therapeutic Approach in Wound Healing 141Richa Dayaramani, Soma Jana, Bratati Bandyopadhyay, Amlan Bishal and Subhashis Debnath6.1 Introduction 1426.2 Physiology of Wound-Healing Process 1436.3 Biology of Stem Cells and their Role in Wound Healing 1456.4 Stem Cell Therapy for Wound Healing and Histopathological Studies 1486.5 Stem Cell Delivery Mechanisms for Wound Healing 1486.6 Clinical Uses of Stem Cell Therapy in Wound Healing 1496.7 Recent Developments and Technologies in Stem Cell Research for Wound Healing 1506.8 Challenges in Stem Cell Treatment 1516.9 Potential Future Applications of Stem Cell–Derived Products in the Use of Stem Cells for Wound Healing 1546.10 Conclusion 1577 Stem Cell Therapy: Skin Aging Blocking 163Dipanjana Ash, Sohini Sen, Sneha Shaw, Ayon Dutta, Leena Kumari and Swarupananda Mukherjee7.1 Introduction 1647.2 Stem Cell: An Overview 1657.3 Mechanisms of SC Action in Skin Regeneration 1707.4 Preclinical Applications of SC in Skin Aging 1737.5 Clinical Applications of SC in Skin Aging 1757.6 Challenges and Considerations 1777.7 Future Directions and Innovations 1817.8 Conclusion 1828 Future Window of Stem Cells in Skin Regeneration and Rejuvenation: Current Status and Future Aspect 195Vivek Barik, Bramhajit Chatterjee, Snigdha Chatterjee, Swarupananda Mukherjee and Piyali Khamkat8.1 Introduction 1968.2 Types of SCs Used in Skin Regeneration and Rejuvenation 1988.3 Emerging Technologies and Innovations 2028.4 Challenges in SC-Based Therapies 2058.5 Future Directions of SCs in Skin Regeneration and Rejuvenation 2068.6 Current Clinical Trials Updates 2088.7 Regulatory Challenges for SC-Based Therapies 2108.8 Conclusion 2119 Stem Cell Therapy in Dermatology: Challenges and Opportunities 219Garima Chandak, Sumel Ashique, Shubham Kumar, Narendra Kumar Pandey, Dileep Singh Baghel, Bimlesh Kumar, Saurabh Singh and Omji Porwal9.1 Introduction 2209.2 Types of Stem Cells in Dermatology 2249.3 Mechanisms of Action 2259.4 Current Applications of Stem Cell Therapy in Dermatology 2309.5 Advances in Stem Cell Delivery Systems 2359.6 Challenges in Stem Cell Therapy for Dermatology 2389.7 Opportunities and Emerging Trends 2429.8 Preclinical and Clinical Studies 2469.9 Regulatory and Ethical Considerations 2559.10 Future Directions 2569.11 Conclusion 25710 Clinical Significance and Regulatory Aspects of Stem Cell Therapy 271Debasmita Paul, Karan Kr. Das, Abhijit Ghosh, Soukat Chandra and Shaileyee Das10.1 Introduction 27210.2 Definition and Types of Stem Cells 27410.3 Mechanisms of Action of Stem Cell Therapy 27610.4 Future Perspectives 29110.5 Conclusions and Future Directions 29311 Translational Research for Dermatological Stem Cell Therapy 301Mishra Bharti, Khan Anam, Gothalwal Ragini, Jaiswal Prashansa and Kotnis Ashwin11.1 Introduction 30111.2 Mechanism of Stem Cell Action in Skin Regeneration and Healing 30411.3 Current Applications of Stem Cell Therapy in Dermatology 30711.4 Safety and Challenges in Translating Stem Cell Research to Clinical Practice 31011.5 Conclusion and Prospects for the Future 31212 In Vitro and In Vivo Model of Stem Cell Therapy in Dermatological Diseases 321Sneha Das, Pradip Jana, Mohini Mondal, Mainak Chatterjee and Moitreyee Chattopadhyay12.1 Introduction 32212.2 Current and Future Perspectives of SC Therapy in Dermatology by In Vitro and In Vivo Models 32512.3 In Vitro Models for SC Therapy in Dermatological Diseases 32812.4 Various Animal Model for In Vivo in Dermatological Diseases 33112.5 Analytical and Numerical Solutions to the Various Models 33412.6 Conclusions and Future Directions 33513 Preclinical and Clinical Trials and Case Studies Involved in Stem Cell Therapy in Dermatological Diseases 341Rony Mandal, Somali Gorai and Sajal Kumar Jha13.1 Introduction 34213.2 Forms of Stem Cell Therapy 34313.3 Role of Autoimmune System in Dermatological Skin Problem 34713.4 Therapeutic Value of Stem Cell in Different Allergic Skin Disease 35013.5 Role of Cutaneous Stem Cells in Regeneration of Different Tissues 35213.6 Advantages of Stem Cell Therapy for Different Dermatological Diseases 35413.7 Different In Vivo and In Vitro Models for Preclinical SCT 35613.8 Preclinical Test Method for Different Skin Disease 36013.9 FDA-Approved Clinical Phase Trial Drugs for Dermatological Disease 36413.10 Conclusions and Future Directions 365References 366Bibliography 370Index 371