Particle-Lung Interactions

Peter Gehr, University of Berne, Switzerland. Christian Mühlfeld, University of Giessen, Germany. Barbara Rothen-Rutishauser, University of Berne, Switzerland. Fabian Blank University of Berne, Switzerland.

• Introduction Preface Part 1: Structure and Function of the Lung 1. Functional Aspects of Lung Structure as Related to Interaction with Particles Part 2: Particle Characteristics2. Ambient Tropospheric Particles 3. Manufactured Nanoparticles 4. Particulate Carriers for Pulmonary Drug Delivery Part 3: Inhalation of Particles 5. Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Sized Particles in the Respiratory Tract Part 4: Health Effects of Particle Inhalation6. The Epidemiology of Particle Health Effects 7. Cardiovascular Consequences of Particles 8. Autonomic Mediation of the Cardiac Responses to Particle Exposure 9. Effects of Airborne Particles on Respiratory Viral Infection 10. Airborne Particles and Structural Remodeling of the Lungs Part 5: Cellular and Molecular Mechanisms of Particle Health Effects 11. Effect of Particles on Mucus and Mucociliary Clearance 12. The Role of Surfactant in Particle Exposure 13. Nanoparticle–Cell Membrane Interactions 14. Mechanisms and Processes Underlying Toxicological Responses to Particles 15. Aeroallergen-Lung Interactions 16. Dose-Response Relationships