Animal Clinical Chemistry

... a welcome update to the 1996 first edition. It is great to see that the new edition retains the highly useful (and extensive) reference list at the end of each chapter. ... Overall, this book represents a valuable addition to the toxicologist's armory, both for those new in the field and those a bit longer in the tooth! -Paul Baldrick, in The British Toxicology Society Newsletter, Winter 2009, Issue 35 Praise for the Previous Edition: ... a very well written and concise book, which ought to reach a much wider audience than toxicologists. It addresses normal and abnormal clinical chemistry of laboratory animals and is thus of relevance to the large segment of the biomedical research community making use of animal models in their research. -Jann Hau, Chair of Comparative Medicine and Head of the Department of Experimental Medicine, University of Copenhagen and State Hospital ... produced to a high standard, consistent style, and of clear relevance to toxicology ... a timely, practical, and useful addition to the literature. It is highly recommended both for toxicology courses and functional laboratories and will no doubt be regarded as a standard text in the field. -Phillip Harvey, AgrEvo UK Ltd, in The British Toxicology Society Newsletter, December 1996

• Introduction. General Enzymology. Assessment of Hepatotoxicity. Assessment of Nephrotoxicity. Assessment of Gastrointestinal and Pancreatic Toxicities. Fluid Balance, Electrolytes, and Mineral Metabolism. Assessment of Cardiotoxicity and Myotoxicity. Proteins. Lipids. Assessment of Endocrine Toxicity. Assessment of Neurotoxicity. Preanalytical Variables. Analytical Variables and Biosafety. Data Processing and Interpretation. References for Laboratory Animal Clinical Chemistry Data. Appendix A References for Laboratory Animal Clinical Chemistry Data. Appendix B SI Unitage and Conversions. Appendix C "Expectable" Ranges for Plasma/Serum. Appendix D General Abbreviations. Appendix E Some Common Biochemical Abbreviations. Index.