Mitochondria

Dr. Stephen W. Schaffer is a professor at the University of South Alabama. He is a member of the editorial board of Molecular and Cellular Biochemistry. Dr. M.-Saadeh Suleiman is a professor at the University of Bristol, UK. His research includes investigating the role of metabolites and ionic species in myocardial protection, with special emphasis on amino acids, mitochondria, Ca2+ loading and reactive oxygen species.

• Mitochondrial Metabolism.- Regulation of Mitochondrial Respiration in Heart Muscle.- Regulation of Fatty Acid Oxidation of the Heart.- Regulation of Mitochondrial Fuel Handling by the Peroxisome Proliferator-Activated Receptors.- Molecular Structure of the Mitochondrial Citrate Transport Protein.- Regulation of Pyruvate and Amino Acid Metabolism.- Amino Acids and the Mitochondria.- The Dynamic Nature of the Mitochondria.- Mechanotransduction of Shear-stress at the Mitochondria.- Mitochondria as Initiators of Cell Signaling.- Formation of Reactive Oxygen Species in Mitochondria.- Mitochondrial Calcium: Role in the Normal and Ischaemic/Reperfused Myocardium.- Mitochondrial Ion Channels.- Mitochondria as Initiators of Cell Death.- The Mitochondrial Permeability Transition Pore – from Molecular Mechanism to Reperfusion Injury and Cardioprotection.- The Apoptotic Mitochondrial Pathway – Modulators, Interventions and Clinical Implications.- The Role of Mitochondria in Necrosis Following Myocardial Ischemia-Reperfusion.- Mitochondria as Modulators of Cell Death.- Mitochondria and Their Role in Ischemia/Reperfusion Injury.- Mitochondrial DNA Damage and Repair.