Bokus
Yang V. Li, John H. Zhang - Metal Ion in Stroke, Inbunden

Inbunden, Engelska, 2012

Metal Ion in Stroke

Av Yang V. Li, John H. Zhang

Del i serien Springer Series in Translational Stroke Research

2221 kr

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Beskrivning
Stroke is a major cause of death and disability in the U.S. and worldwide. A variety of pathophysiologic episodes or cellular medications occur following a stroke, and knowledge of these aftermath events can lead to potential therapeutic strategies that may reverse or attenuate stroke injury. Cellular events that occur following stroke include the excessive releases of excitatory amino acids, alterations in the genomic responses, mitochondrial injury producing reactive oxygen and nitrogen species (ROS), and secondary injury, often in the setting of reperfusion.
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From the reviews: "This is a comprehensive book about the role of ions and anions in neurotransmission, cerebral ischemia, subarachnoid hemorrhage, trauma etc. Each chapter is devoted to the indication of mediators related to channel and mitochondrial pathophysiology. ... I recommend this book to neurologists, neurosurgeons, biochemists, and neurophysiologists. Students will be greatly helped by this book, showing that cofactors can be toxic, but at micromolar ranges be beneficial to the stroked brain in small vessel disease." (Joseph J. Grenier, Amazon.com, May, 2014)

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