Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.
Beskrivning
The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Because of a central role of endoplasmic reticulum, calreticulin and calnexin in virtually all cellular functions, the book should be of interest to everyone in the biological sciences.
0.- Preface.- Abbreviations.- 1. Introduction to Calreticulin.- 2. Biochemical and Molecular Properties of Calreticulin.- 3. A Chaperone System for Glycoprotein Folding: The Calnexin/Calreticulin Cycle.- 4. Calnexin, an ER Integral Membrane Chaperone in Health and Disease.- 5. Sub-Cellular Distribution of Calreticulin.- 6. Calnexin and Calreticulin, Molecular Chaperones of the Endoplasmic Reticulum.- 7. Roles of Calreticulin and Calnexin in Myeloperoxidase Synthesis.- 9. The Role of Calnexin and Calreticulin in MHC Class I Assembly.- 10. Calreticulin and the Endoplasmic Reticulum in Plant Cell Biology.- 11. Modulation of Calcium Homeostasis by the Endoplasmic Reticulum in Health and Disease.- 12. Calnexin and Calreticulin, ER Associated Modulators of Calcium Transport in the ER.- 13. ER Calcium and ER Chaperones: New Players in Apoptosis?.- 14. Calreticulin in Cytotoxic Lymphocyte-Mediated Cytotoxicity.- 15. A Role for Calreticulin in the Clearance of Apoptotic Cells and in the Innate Immune System.- 17. Calreticulin’s Role(s) in Autoimmune Disorders.- 18. Cell Surface Calreticulin: Role in Signaling Thrombospondin Anti-Adhesive Activity.- 19. Calreticulin Regulation of Lung Endothelial NOS Activity.- 20. Role of Calreticulin in Leishmania Parasite Secretory Pathway and Pathogenesis.- 21. The Hookworm Calreticulin Conundrum.- 22. Calreticulin in C. elegans.- 23. Calreticulin Deficient Mouse.- 267.- Appendix II: Amino Acid Sequence of Calreticulin.
