Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

Häftad, Engelska, 2012

Del i serien Medical Science Symposia Series

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Beskrivning

Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control.

Produktinformation

Utgivningsdatum:2012-10-14
Mått:155 x 235 x 11 mm
Vikt:306 g
Format:Häftad
Språk:Engelska
Serie:Medical Science Symposia Series
Antal sidor:172
Förlag:Springer-Verlag New York Inc.
ISBN:9781461354277

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik
Klinisk medicin och internmedicin inom Medicin

Innehållsförteckning

1. Peroxisome Proliferator Activated Receptor Alpha Coordinates Intermediary Metabolism During Fasting.- 2. Design, Structure, and Function of Novel PPAR Ligands.- 3. Functions of PPAR Gamma in Macrophages and Atherosclerosis.- 4. PPARs and Atherogenesis: Mediators or Modulators of the Inflammatory Response in the Vessel Wall?.- 5. Role of PPARs in Inflammation, Atherosclerosis, and Thrombosis.- 6. Effects of Thiazolidinediones on Vascular Reactivity and Endothelial Dysfunction.- 7. Activation of Human PPAR Subtypes by Pioglitazone.- 8. PPAR? Mechanism of Action Studies.- 9. The Role of PPAR? in Fatty Acid Metabolism and Hepatocarcinogenesis: Studies with PPAR?-Null Mice.- 10. PPAR?, Lipoprotein Metabolism, Metabolic Disease, and Atherosclerosis.- 11. PPAR? and Atherosclerosis.- 12. Regulation of CD36 by PPAR?: Pro- or Anti-atherogenic?.- 13. Anti-inflammatory Properties of High Density Lipoproteins.- 14. The Low-HDL Syndrome: Epidemiology and Pathophysiology.- 15. Diabetes: A Growing CHD Epidemic.- 16. Influence of PPARs on Muscle Lipid Metabolism and Insulin Resistance.- 17. PPAR? in Adipogenesis and Insulin Resistance.- 18. Pharmacology of a Selective Peroxisome Proliferator-Activated Receptor ? Agonist, GW501516, in Obese Dyslipidemic Primates.- 19. PPAR?: A Regulator of Growth and Differentiation.- 20. Peroxisome Proliferator Activator Receptor Gamma Agonists Inhibit the Development of Atherosclerosis in Low Density Lipoprotein Receptor-Deficient Male Mice.- 21. Are Thiazolidinediones Superior to Standard Therapy in the Treatment of Type 2 Diabetes?.- 22. PPAR? Ligands and Intestinal Inflammation.- 23. Inflammatory Mechanisms in Alzheimer’s Disease: ?-Amyloid-Stimulated Proinflammatory Responses Are Blocked by PPAR? Agonists.