Nanoscale Imaging of Synapses

New Concepts and Opportunities

AvU. Valentin Nägerl,Antoine Triller

Inbunden, Engelska, 2014

Del i serien Neuromethods

1 637 kr

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Beskrivning

Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. The proposed volume brings together leading researchers to review these exciting new techniques and their application in neurobiological research.

Produktinformation

Utgivningsdatum:2014-02-05
Mått:178 x 254 x 15 mm
Vikt:596 g
Format:Inbunden
Språk:Engelska
Serie:Neuromethods
Antal sidor:231
Upplaga:2014
Förlag:Humana Press Inc.
ISBN:9781461491781

Utforska kategorier

Teknik: allmänt inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik
Medicinsk bildbehandling inom Medicin

Innehållsförteckning

Preface.- Nanoscale imaging of protein molecules at the postsynaptic densit.- Electron tomography for the study of synaptic ultrastructure in fixed brain sections.- Time-resolved electron microscopy: coupling optogenetics with high-pressure freezing.- Investigating AMPA receptors diffusion and nanoscale organization at synapses with high density single molecule tracking methods.- Visualising the ultra-structures and dynamics of synapses by single molecule nanoscopy.- Live-cell PALM of intracellular proteins in neurons.- Monitoring nanoscale mobility of small molecules with time-resolved fluorescence anisotropy imaging.- Imaging signalling transduction in single dendritic spines.- Imaging-based measures of synaptic tenacity.- Zooming in on the (peri)synaptic extracellular matrix.- Two-photon STED microscopy for imaging synapses and glia in acute brain slices.- Index.