MicroRNA Target Identification

Methods and Protocols

AvAlessandro Laganà

Inbunden, Engelska, 2019

Del i serien Methods in Molecular Biology

1 853 kr

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Beskrivning

This detailed book provides a comprehensive state-of-the-art presentation of all aspects of miRNA target identification, from the prediction of miRNA binding sites on their target molecules to their experimental validation and downstream functional analysis.

Produktinformation

Utgivningsdatum:2019-04-09
Mått:178 x 254 x 26 mm
Vikt:896 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:359
Förlag:Humana Press Inc.
ISBN:9781493992065

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik
Medicinsk genetik inom Medicin

Innehållsförteckning

A Practical Guide to miRNA Target Prediction.- miRandb: A Meta-Database of Online Resources of miRNA and miRNA Targets.- Sfold Tools for MicroRNA Target Prediction.- The Role of Tertiary Structure in MicroRNA Target Recognition.- Protocols for miRNA Target Prediction in Plants.- Improving miRNA-Target Prediction Using CLASH Data.- Integration of Omics Data to Identify Cancer-Related MicroRNA.- Functional Analysis of Genetic Variants and Somatic Mutations Impacting MicroRNA-Target Recognition: Bioinformatics Resources.- Construction and Analysis of miRNA Regulatory Networks.- Identification of Disease-miRNA Networks across Different Cancer Types Using SWitchMiner (SWIM).- Computational Methods to Investigate the Impact of miRNAs on Pathways.- Consensus Target Prediction with Enrichment Analysis for MicroRNAs Harboring Editing Sites and Other Variations.- A Roadmap for the Computational Prediction and Experimental Validation of Competitive Endogenous RNAs.- Investigating miRNA-lncRNA Interactions: Computational Tools and Resources.- Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks.- Inconsistencies and Limitations of Current MicroRNA Target Identification Methods.- Experimental Validation of MicroRNA Targets: Luciferase Reporter Assay.- Experimental Validation of MicroRNA Targets: Mutagenesis of the Binding Regions.- Experimental Validation of MicroRNA Targets: Analysis of MicroRNA Targets through Western Blotting.