Genotoxicity Assessment

Methods and Protocols

AvAlok Dhawan,Mahima Bajpayee

Häftad, Engelska, 2020

Del i serien Methods in Molecular Biology

1 314 kr

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Beskrivning

Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, tips on troubleshooting and avoiding known pitfalls.

Produktinformation

Utgivningsdatum:2020-09-02
Mått:178 x 254 x 22 mm
Vikt:735 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:378
Upplaga:2
Förlag:Humana Press Inc.
ISBN:9781493996483

Utforska kategorier

Innehållsförteckning

In Vitro Mouse Lymphoma Cell (L5178Y Tk+/- -3.7.2.C) Forward Mutation Assay.- Erythrocyte-Based Pig-a Gene Mutation Assay.- Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.- In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests.- Dicentric Chromosome Assay (DCA) and Cytokinesis-Block Micronucleus (CBMN) Assay in the Field of Biological Dosimetry.- Chromosomal Aberration Test in Human Lymphocytes.- In Vivo Micronucleus Assay in Mouse Bone Marrow.- Micronucleus Cytome Assays in Human Lymphocytes and Buccal Cells.- Micronucleus Analysis by Flow Cytometry.- Hen’s Egg Test for Micronucleus Induction (HET-MN).- Comparative Genomic Hybridization (CGH) in Genotoxicology.- The Comet Assay: Assessment of In Vitro and In Vivo DNA Damage.- The Comet Assay in Human Biomonitoring.- The Comet Assay in Marine Animals.- Multicolour Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers.- Detection of DNA Double Strand Breaks Using Pulse Field Gel Electrophoresis.- Detection of UV-Induced Thymine Dimers.- Micronucleus Assay with Tetrad Cells of Tradescantia.- The Wing-Spot and the Comet Tests as Useful Assays for Detecting Genotoxicity in Drosophila.- In Silico Approaches in Predictive Genetic Toxicology.