James F. Childress is the John Allen Hollingsworth Professor of Ethics at the University of Virginia. Eric M. Meslin is director of the Indiana University Center for Bioethics. Harold T. Shapiro is president emeritus, Princeton University and a professor of economics and public affairs in the Woodrow Wilson School of Public and International Affairs.

"There can be little doubt that the 1979 Belmont Report was a key document in the development of national policy on human subject research. Its history and its importance are too little known. This book, a splendid and probing collection about the Report, is an important study, readable and interesting. Human subject research remains a difficult and contentious area. This book helps to show why, and will help to bring greater light to the ongoing debate." - Daniel Callahan, director of international programs, The Hastings Center "Twenty-five years after publication, the Belmont Report and the principles it espoused remain the most influential events in biomedical research worldwide. These retrospective reflections, by participants in the report's formulations, offer frank and updated insights into the genesis and evolution of the report - and especially of its three famous principles. Given today's renewed scrutiny of human subject research, these essays will interest clinical investigators, policymakers, legislators, and the general public." - Edmund D. Pellegrino, professor emeritus of medicine and medical ethics, Georgetown University"

• Introduction PART I: BACKGROUND AND ORIGINS OF THE BELMONT REPORT 1. On the Origins and Future of the Belmont Report Albert R. Jonsen 2. The Origins and Evolution of the Belmont ReportTom L. Beauchamp PART II: THE BELMONT PRINCIPLES: INFLUENCE & APPLICATION3. The Dog in the Night-Time: Or the Curious Relationship of the Belmont Report and the President's Commission Alexander M. Capron 4. Beyond Belmont: Trust, Openness, and the Work of the Advisory Committee on Human Radiation ExperimentsRuth R. Faden, Anna Mastroianni, and Jeffrey P. Kahn 5. Relating to History: The Influence of the National Commission and Its Belmont Report on the National Bioethics Advisory CommissionHarold T. Shapiro and Eric M. Meslin 6. The Principles of the Belmont Report: How Have Respect for Persons, Beneficence, and Justice Been Applied in Clinical Medicine?Eric J. Cassell Part III: THE BELMONT PRINCIPLES: POSSIBILITIES, LIMITATIONS, AND UNRESOLVED QUESTIONS7. We Sure We Are Older But Are We Wiser?Karen Lebacqz 8. Toward a More Robust Autonomy: Revisiting the Belmont ReportLarry R. Churchill 9. The National Commission's Ethical Principles With Special Attention to BeneficenceRobert J. Levine 10. Justice beyond BelmontPatricia A. King 11. Belmont Revisited Through a Feminist LensSusan Sherwin 12. Protecting Communities in Research: From a New Principle to Rational ProtectionsEzekiel J. Emanuel and Charles Weijer 13. Ranking, Balancing, or Simultaneity: Resolving Conflicts Among the Belmont PrinciplesRobert M. Veatch 14. Specifying, Balancing, and Interpreting Bioethical PrinciplesHenry S. Richardson 15. Max Weber Meets the Belmont Report: Toward a Sociological Interpretation of PrinciplismJohn H. Evans Epilogue: Looking Back to Look Forward James F. Childress Appendix: The Belmont Report Contributors Index

James F. Childress is the John Allen Hollingsworth Professor of Ethics at the University of Virginia. Eric M. Meslin is director of the Indiana University Center for Bioethics. Harold T. Shapiro is president emeritus, Princeton University and a professor of economics and public affairs in the Woodrow Wilson School of Public and International Affairs.

"There can be little doubt that the 1979 Belmont Report was a key document in the development of national policy on human subject research. Its history and its importance are too little known. This book, a splendid and probing collection about the Report, is an important study, readable and interesting. Human subject research remains a difficult and contentious area. This book helps to show why, and will help to bring greater light to the ongoing debate." - Daniel Callahan, director of international programs, The Hastings Center "Twenty-five years after publication, the Belmont Report and the principles it espoused remain the most influential events in biomedical research worldwide. These retrospective reflections, by participants in the report's formulations, offer frank and updated insights into the genesis and evolution of the report - and especially of its three famous principles. Given today's renewed scrutiny of human subject research, these essays will interest clinical investigators, policymakers, legislators, and the general public." - Edmund D. Pellegrino, professor emeritus of medicine and medical ethics, Georgetown University"

• Introduction PART I: BACKGROUND AND ORIGINS OF THE BELMONT REPORT 1. On the Origins and Future of the Belmont Report Albert R. Jonsen 2. The Origins and Evolution of the Belmont ReportTom L. Beauchamp PART II: THE BELMONT PRINCIPLES: INFLUENCE & APPLICATION3. The Dog in the Night-Time: Or the Curious Relationship of the Belmont Report and the President's Commission Alexander M. Capron 4. Beyond Belmont: Trust, Openness, and the Work of the Advisory Committee on Human Radiation ExperimentsRuth R. Faden, Anna Mastroianni, and Jeffrey P. Kahn 5. Relating to History: The Influence of the National Commission and Its Belmont Report on the National Bioethics Advisory CommissionHarold T. Shapiro and Eric M. Meslin 6. The Principles of the Belmont Report: How Have Respect for Persons, Beneficence, and Justice Been Applied in Clinical Medicine?Eric J. Cassell Part III: THE BELMONT PRINCIPLES: POSSIBILITIES, LIMITATIONS, AND UNRESOLVED QUESTIONS7. We Sure We Are Older But Are We Wiser?Karen Lebacqz 8. Toward a More Robust Autonomy: Revisiting the Belmont ReportLarry R. Churchill 9. The National Commission's Ethical Principles With Special Attention to BeneficenceRobert J. Levine 10. Justice beyond BelmontPatricia A. King 11. Belmont Revisited Through a Feminist LensSusan Sherwin 12. Protecting Communities in Research: From a New Principle to Rational ProtectionsEzekiel J. Emanuel and Charles Weijer 13. Ranking, Balancing, or Simultaneity: Resolving Conflicts Among the Belmont PrinciplesRobert M. Veatch 14. Specifying, Balancing, and Interpreting Bioethical PrinciplesHenry S. Richardson 15. Max Weber Meets the Belmont Report: Toward a Sociological Interpretation of PrinciplismJohn H. Evans Epilogue: Looking Back to Look Forward James F. Childress Appendix: The Belmont Report Contributors Index

James F. Childress is the John Allen Hollingsworth Professor of Ethics at the University of Virginia. Eric M. Meslin is director of the Indiana University Center for Bioethics. Harold T. Shapiro is president emeritus, Princeton University and a professor of economics and public affairs in the Woodrow Wilson School of Public and International Affairs.

"There can be little doubt that the 1979 Belmont Report was a key document in the development of national policy on human subject research. Its history and its importance are too little known. This book, a splendid and probing collection about the Report, is an important study, readable and interesting. Human subject research remains a difficult and contentious area. This book helps to show why, and will help to bring greater light to the ongoing debate." - Daniel Callahan, director of international programs, The Hastings Center "Twenty-five years after publication, the Belmont Report and the principles it espoused remain the most influential events in biomedical research worldwide. These retrospective reflections, by participants in the report's formulations, offer frank and updated insights into the genesis and evolution of the report - and especially of its three famous principles. Given today's renewed scrutiny of human subject research, these essays will interest clinical investigators, policymakers, legislators, and the general public." - Edmund D. Pellegrino, professor emeritus of medicine and medical ethics, Georgetown University"

• Introduction PART I: BACKGROUND AND ORIGINS OF THE BELMONT REPORT 1. On the Origins and Future of the Belmont Report Albert R. Jonsen 2. The Origins and Evolution of the Belmont ReportTom L. Beauchamp PART II: THE BELMONT PRINCIPLES: INFLUENCE & APPLICATION3. The Dog in the Night-Time: Or the Curious Relationship of the Belmont Report and the President's Commission Alexander M. Capron 4. Beyond Belmont: Trust, Openness, and the Work of the Advisory Committee on Human Radiation ExperimentsRuth R. Faden, Anna Mastroianni, and Jeffrey P. Kahn 5. Relating to History: The Influence of the National Commission and Its Belmont Report on the National Bioethics Advisory CommissionHarold T. Shapiro and Eric M. Meslin 6. The Principles of the Belmont Report: How Have Respect for Persons, Beneficence, and Justice Been Applied in Clinical Medicine?Eric J. Cassell Part III: THE BELMONT PRINCIPLES: POSSIBILITIES, LIMITATIONS, AND UNRESOLVED QUESTIONS7. We Sure We Are Older But Are We Wiser?Karen Lebacqz 8. Toward a More Robust Autonomy: Revisiting the Belmont ReportLarry R. Churchill 9. The National Commission's Ethical Principles With Special Attention to BeneficenceRobert J. Levine 10. Justice beyond BelmontPatricia A. King 11. Belmont Revisited Through a Feminist LensSusan Sherwin 12. Protecting Communities in Research: From a New Principle to Rational ProtectionsEzekiel J. Emanuel and Charles Weijer 13. Ranking, Balancing, or Simultaneity: Resolving Conflicts Among the Belmont PrinciplesRobert M. Veatch 14. Specifying, Balancing, and Interpreting Bioethical PrinciplesHenry S. Richardson 15. Max Weber Meets the Belmont Report: Toward a Sociological Interpretation of PrinciplismJohn H. Evans Epilogue: Looking Back to Look Forward James F. Childress Appendix: The Belmont Report Contributors Index