Nutrition and Immunology

"...this book comes at a timely moment, when the impact of nutrition and immunology is being widely felt because of the AIDS epidemic...There are a number of novel areas treated in this book that illustrate the changing tide and the great need to understand the molecular basis of interactions, in addition to understanding and performing simple dietary assessment."-Foreword by Ranjit Kumar Chandra, DSc, PhD, MD "A wide range of topics are covered, beginning with chapters on nutritional assessment and nutrient requirements for a properly functioning immune system. The editors conclude with a series of discussions on nutrition and its role in a wide variety of clinical issues, ranging from a chapter on breast milk to the role of diet in various diseases. Chapters on alternative medicines and their effect on immunity are also included. This is a wealth of information that nutritionists, immunologists, and physicians may not always think about. Because of the many topics that are discussed, a large amount of information is provided in an accessible format with good references... Issues that are generally not included in immunology courses are compiled here, and probably should be. Most of the chapters are easy to read and contain some thought provoking material for discussion. This book could easily form the basis for a graduate level course.."-4 Stars!, Doody's Health Sciences Book Review Journal "This unique book, authored by leading investigators in the field of nutrition and immune function, is a comprehensive, readable collection for both researchers and clinicians...Ten basic science chapters review the stat-of-the-art with regard to specific nutrients and their impact on immunity...All of the basic science chapters have outstanding figures of metabolic pathways, and nicely summarize the current understanding of cellular mechanisms. The chapters that examine specific clinical issues include several noteworthy contributions, particularly the chapters on nutrition and common oral diseases, and several superb reviews of nutritional therapy approaches to inflammatory and autoimmune diseases. There are also excellent chapters on AIDS, cancer, diabetes, allograft rejection, food toxicology, nutrition/immunity interactions, perioperative feeding, immune consequences of breast feeding, and a review of antioxidants in the aging immune system...this well-written, authoritative, and comprehensive book is a welcome addition and valuable reference for clinicians and investigators interested in modifying immune responses through nutrition." -Quarterly Review of Biology "This is a substantial and well produced book in both physical and figurative senses, packed with information and references...provides a comprehensive review of the role of nutrition in health, with a major focus on how diet can reduce the onset and progression of numerous chronic diseases."-Nutrition and Health "...this text is outstanding. If focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge ...The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin "Of the recent books designed for this purpose, this text is outstanding. It focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge...The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin "With contributions by 67 authors the editors of "Nutrition and Immunology" try to classify and evaluate the enormous and complex flood of data as one the well-known relationship between nutrition and state of immunity... Against the background of growing "food-design" the relationships between nutritional and immunological research reach a completely new dimension. In the opinion of the authors this will require the establishment of a new field of nutritional science: nutritional immunology, which will be based on interdisciplinary research...The strong point of the book is the convincing extensive discussion of mainly clinical findings on the relationship between nutrition and immunity." - Nahrung/Food

• I. Nutritional Assessment.- 1 Application and Interpretation of Commonly Used Nutritional Assessment Techniques.- 2 Evaluating Malnutrition: What Should the Physician Look For?.- 3 Evaluation of the Immune System in the Nutritionally At-Risk Host.- II. Specific Nutrient Requirements (Normal Populations; Populations with Low Intakes, Including Teens, Females, Elderly...).- 4 Caloric Intake: Sources, Deficiencies, and Excess — An Overview.- 5 Protein and Amino Acids.- 6 Specific Nutrient Requirements: Trace Elements.- 7 Vitamins: Overview and Metabolic Functions.- 8 ?-Lipoic Acid: The Metabolic Antioxidant.- 9 Defining the Role of Dietary Phytochemicals in Modulating Human Immune Function.- 10 Dietary n-3 Polyunsaturated Fatty Acids Modulate T-Lymphocyte Activation: Clinical Relevance in Treating Diseases of Chronic Inflammation.- 11 Nucleotides.- III. Nutrient-Immune Interactions.- 12 Impact of Nutritional Status on Immune Integrity.- 13 Nutritional Modulation of Inflammation by Polyunsaturated Fatty Acids/Eicosanoids.- IV. Clinical Issues.- 14 Immunological Considerations of Breast Milk.- 15 Clinical Issues: Childhood Illnesses, Vaccinations, and Nutritional Status.- 16 Protein-Energy Malnutrition and Infectious Disease: Synergistic Interactions.- 17 Lipids, Inflammatory Cytokines, and Endothelial Cell Injury.- 18 Nutrition and Allergy.- 19 Adverse Reactions to Foods.- 20 Perioperative Feeding: Nutrition and Immunity.- 21 Alcohol and Immune Function.- 22 Cigarette Smoking, Substance Abuse, Nutritional Status, and Immune Function.- 23 Nutrition, Immunity, and Alternative Medicine.- 24 Obesity and Immunity.- 25 Diabetes and Immunity.- 26 Nutritional Modulation of Autoimmune Diseases.- 27 Autoimmune Diseases of the Digestive Tract.- 28 Diet and Allograft Rejection.- 29Food Toxicology and Immunity.- 30 Interactions Between Nutrition and Immunity: Lessons from Animal Agriculture.- 31 Cancer and Nutrition.- 32 AIDS.- 33 Aging: Nutrition and Immunity.- 34 Role of Nutrition in Common Oral Diseases.- 35 The Anti-Inflammatory Effects of Chinese Herbs, Plants, and Spices.- 36 The Influence of Probiotic Organisms on the Immune Response.- 37 Nutritional Effects on the Pathogen Genome and Phenotypic Expression of Disease.- V. Future Directions.- 38 Whither Nutrition and Immunology Interactions Toward the Next Millennium? What is Past is Prologue.