M. Eric Gershwin – författare
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56 produkter
56 produkter
E-bok
Engelska, 20062 673 kr
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Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels.New to This Edition:* Tissue-specific interventions to arrest or "cure" autoimmune disease* Bone marrow eradication and replacement* Both basic science and clinical medicine is covered* Boxed points to emphasize key features of each chapter
E-bok
Engelska, 20112 044 kr
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Autoantibodies was published and presented in November 2006 at the International Congress of Autoimmunity in Sorrento, a small town in Campania, Italy. The Congress also celebrated the 100th anniversary of the first routine test for autoantibodies. An autoantibody is a type of antibody that is produced by the immune system and that fights one or more of a person''s own proteins. These autoantibodies cause autoimmune diseases such as lupus erythematosus. The authors and editors of this book provide a critical review of autoantibodies and their primary functions. They cite a number of major developments in the field of autoantibodies, including the detection of autoantibodies in which a healthy person is a carrier; the discovery that autoantibodies can be both pathogenic and protective in some cases; and the development of a device that will help monitor and detect a specific autoantibody using a small amount of serum and proteomic arrays. Aside from the pathogenic and protective autoantibodies, the book also discusses irrelevant autoantibodies, as these may be relevant for future research. It also addresses the importance of the autoantibodies in a person''s body. Clinical physicians, as well as scientists interested in the significance of autoantibodies in the human body, will find this book relevant. It will also be of interest to those who suffer from an autoimmune disease.- Incudes and exhaustive list of autoantibodies not covered by other publications- Short reviews can easily be checked for quick reference information- Both basic and clinical aspects are covered
E-bok
Engelska, 20132 201 kr
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Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.- Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy- Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases- Keeps readers abreast of current trends and emerging areas in the field- Ensures that content is not only up-to-date, but applicable and relevant
E-bok
Engelska, 20194 068 kr
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The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P''s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments.The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.- Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy- Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases- Keeps readers abreast of current trends and emerging areas in the field- Ensures that content is not only up-to-date, but applicable and relevant- Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy
E-bok
PDF, Engelska, 2012692 kr
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This book deals with autoimmune disease in humans (as opposed to autoimmunity itself). It discusses the biological basis of disease at the molecular, genetic, cellular, and epidemiologic levels. It also describes the clinical problems of diagnosis, prognosis, and treatment. The intended audience includes physicians of all specialties in practice, physicians in training such as house staff and fellows, and medical students. It will also be valuable for basic scientists and graduate students interested in the solution of important clinical problems. The book concentrates on topics that have grown or changed dramatically since publication of The Autoimmune Diseases.
Inbunden, Engelska, 2024
3 771 kr
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**Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.
E-bok
Engelska, 20245 377 kr
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**Selected for 2025 Doody''s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P''s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.- Provides new research on autoimmune diseases, their diagnosis, prevention, and therapy- Covers a complete range of all common, rare and new autoimmune diseases, including cancer and COVID- Extensively revised with 75% new material based on autoimmunity, developments in the different diagnosis and therapies for these autoimmune diseases, and a completely updated description of the different diseases- Supplemented with a website that hosts a Podcast per chapter
Inbunden, Engelska, 2013
1 889 kr
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Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value.
The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.
Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis Includes clinical applications for each autoantibody along with general information Organized by disease and disorder type, by autoantibody family, and completely cross-referenced
E-bok
Engelska, 20132 123 kr
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Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value.The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.- Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis- Includes clinical applications for each autoantibody along with general information- Organized by disease and disorder type, by autoantibody family, and completely cross-referenced
Inbunden, Engelska, 1992
484 kr
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In this commonsense book, Dr. Gershwin and Dr. Klingelhofer offer sensible, practical strategies for identifying the substances that cause allergies (allergens), the symptoms they cause, ways exposure to allergens can be avoided or reduced, and ways you can relieve the symptoms. Living Allergy Free also treats some reactions that are commonly assumed to be allergies, but are really sensitivity or irritant reactions, shows how they can be distinguished from true allergies, and tells you what to do about them. If you suffer from allergies - or if you think you do - Living Allergy Free is just what the doctor would order!
Inbunden, Engelska, 1998
1 669 kr
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Seasoned clinicians comprehensively yet succinctly summarize their years of experience in the diagnosis and treatment of acute and chronic pain across a wide variety of medical conditions. Drawing on their extensive personal knowledge of internal medicine family practice rheumatology neurology cardiology as well as of urology oncology neurology physical medicine and gastroenterology they provide all the practical information needed by busy practitioners to initiate appropriate diagnostic tests and therapy- without having to consult other references. Each chapter examines the diseases that can cause pain in the affected area describes appropriate laboratory studies to confirm the diagnosis and discusses in detail the differential diagnosis of the pain. Treatment is presented in practical terms with specific but full information given on medications and dosages. Numerous tables and graphics and organization by anatomical systems allow rapid and easy access to all relevant data.SMP Copy This comprehensive handbook of practical information regarding the diagnosis and treatment of pain is organized to give the busy practitioner rapid access to relevant data for the diagnosis and treatment of pain in every kind of disorder. Written by a multidisciplinary team of highly experienced clinicians the book concisely discusses the differential diagnosis of pain throughout the body describes appropriate diagnostic tests that will confirm the diagnosis and presents the key treatment options in practical terms complete with recommended medications and doses. The Pain Management Handbook will
Inbunden, Engelska, 1998
561 kr
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This complete A Z guide to the effective home treatment of children's allergies contains all the latest information and informed advice that you need to manage your child's symptoms and to help him or her understand and control their own allergies. Written with sympathy and professional understanding gained from their own and their children's severe allergies, Drs. Gershwin and Klingelhofer offer in simple, jargon-free language the best and most up-to-date counsel on how to deal effectively with asthma, hay fever, eczema, food allergies, contact dermatitis, hives, headaches, rhinitis, latex allergies, and more. Here concerned parents will learn how to identify their child's allergic symptoms, how to distinguish these from nonallergic symptoms, the best strategies for avoidance, and what to do about them. If your child suffers from allergies and you want to know more about these often cruel afflictions and what can be done to avoid or treat them, Taking Charge of Your Child's Allergies is just what your doctor would order!
Inbunden, Engelska, 2011
1 337 kr
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Hailed by professional journals and esteemed by primary care physicians, Bronchial Asthma: A Guide for Practical Understanding and Treatment, Sixth Edition, has been fully updated to help physicians face the challenge of diagnosis and management in every variety of patient subpopulation.
E-bok
PDF, Engelska, 20111 659 kr
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Hailed by professional journals and esteemed by primary care physicians, Bronchial Asthma: A Guide for Practical Understanding and Treatment, Sixth Edition, has been fully updated to help physicians face the challenge of diagnosis and management in every variety of patient subpopulation.
E-bok
PDF, Engelska, 2012708 kr
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The comprehensive nature of this text will appeal To many physicians, the study of sinus disease to a wide range of physicians including generalists, reflects a discipline only slightly less interesting otolaryngologists, and allergists. Family physi than a Johnson and Johnson gauze pad, a pursuit cians, internists, pediatricians, and allergists will followed by dilettanti and eccentric professors. To each profit from having a single source that pro others, it represents a subsection of an undefined vides an in-depth review of topics pertaining to discipline that crosses barriers of internal medi sinus diseases. The otolaryngologist will benefit cine, pediatrics, allergy, chest disease, and oto from having a single text that provides a detailed laryngology. To patients, sinus problems are discussion of the many ancillary medical problems synonymous with headaches and a chronic source of morbidity. Yet few physicians have been pre that influence sinus function and, therefore, surgi cal outcome. We hope that all readers will enjoy the pared, until recently, to do much more than pre international choice of authors whose topics have scribe antibiotics, intranasal steroids, antihistamines, been purposely allowed to overlap in an effort to and commiserate for the misery involved. Fortu provide the broadest possible scope of informa nately, this picture shows significant signs of tion. We expect Diseases of the Sinuses to serve as impending remission. The disciplines of clinical immunology, allergy, and otolaryngology have the foundation of an ever-stronger ongoing effort to combat sinus disease.
E-bok
PDF, Engelska, 2012708 kr
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E-bok
PDF, Engelska, 2013598 kr
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In this commonsense book, Dr. Gershwin and Dr. Klingelhofer offer sensible, practical strategies for identifying the substances that cause allergies (allergens), the symptoms they cause, ways exposure to allergens can be avoided or reduced, and ways you can relieve the symptoms. Living Allergy Free also treats some reactions that are commonly assumed to be allergies, but are really sensitivity or irritant reactions, shows how they can be distinguished from true allergies, and tells you what to do about them. If you suffer from allergies-or if you think you do-Living Allergy Free is just what the doctor would order!
E-bok
PDF, Engelska, 20131 565 kr
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Those who do not feel pain seldom think that it is felt. SAMUEL JoHNSON, The Rambler, no. 48 (September 1, 1750) Who among us has not experienced the suffering of a patient with chronic disease, who in addition to the vicissitudes of fatigue, anxiety, and frustration, must also deal with the suffering of pain? Who among us has not considered, and then reconsidered, whether a patient''s complaints are worthy of a narcotic and thence worried about the social and legal implications of chronic use? Who among us has not refused pain medications to our patients for fear that use was turning into abuse? Finally, who among us would not have liked a clinical guide to a myriad of syndromes, all of which have pain as their common denominator, in the hopes of developing some strategy to prioritize treatment. Our purpose in preparing The Pain Management Handbook is to provide the informa tion needed by clinicians to develop strategies that optimize pain management. It is the goal of the editors and authors that the present handbook, above all else, will be clinically useful. Its aim is to provide practical information regarding the diagnosis and treatment of disorders causing pain, along with tables and graphics to provide the busy practitioner with rapid access to relevant data.
Häftad, Engelska, 2012
561 kr
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The comprehensive nature of this text will appeal To many physicians, the study of sinus disease to a wide range of physicians including generalists, reflects a discipline only slightly less interesting otolaryngologists, and allergists.
Häftad, Engelska, 2012
561 kr
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Although the mechanisms and triggers that stimulate and are responsible for the natural history ofasthma are steadily being more clearly defined, uncertainties still surround both the genetic basis and the etiologyofone of the most common syndromes in the world. In fact, it is ofconsider- able concern and interest that the incidence of asthma today appears to be rising. These statistical increments may only reflect an increasing awareness of the disease, or its earlier and more sophisticated diagnosis. More important, however, asthma mortality appears to be increasing. This increase has occurred despite the continuing expansion of a diag- nostic and management information base, and the developmentofnovel andevermoreeffective therapeutic modalities.Severalexplanations have been offered for this increase in mortality, including that it may result from a statistical artifact [based on a change in the coding criteria for asthma from the International ClassificationofDiseases Version 8(ICD- 8) to ICD-9], worsened pollution, delays in seeking medical help, behav- ioral changes, deficits in the asthma education of both patients and primary careproviders, toxicity ofbeta-agonists, and noncompliance with instructions for the proper use of medications. It should also be empha- sized that the increases in both incidence and mortality may be a reflec- tion of accumulating body burdens of environmental toxicants and of increased oxidativedamage. There has clearly beenadegradation ofenvi- ronmental quality. And although considerableattention has been focused on this possibility in both the scientific and lay press, more research in this area is definitely needed.
Häftad, Engelska, 2012
484 kr
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In this commonsense book, Dr. Gershwin and Dr. Klingelhofer offer sensible, practical strategies for identifying the substances that cause allergies (allergens), the symptoms they cause, ways exposure to allergens can be avoided or reduced, and ways you can relieve the symptoms. Living Allergy Free also treats some reactions that are commonly assumed to be allergies, but are really sensitivity or irritant reactions, shows how they can be distinguished from true allergies, and tells you what to do about them. If you suffer from allergies-or if you think you do-Living Allergy Free is just what the doctor would order!
Häftad, Engelska, 2012
1 226 kr
Skickas inom 10-15 vardagar
Those who do not feel pain seldom think that it is felt. Our purpose in preparing The Pain Management Handbook is to provide the informa tion needed by clinicians to develop strategies that optimize pain management.
Häftad, Engelska, 2012
1 115 kr
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Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.
Häftad, Engelska, 2012
1 669 kr
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Our colleagues commented that while the book was eminently suitable for a library, there was still an intellectual need for a more concise volume on nutrition and immunology for health care providers and scientists working at the inter face of delivering therapeutic and/or preventive health care.
E-bok
PDF, Engelska, 20121 408 kr
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Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius''s work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.
Häftad, Engelska, 2012
1 114 kr
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Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius's work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par tial to complete and can be compatible with survival. The consequences of such derange ments run the gamut from subclinical disease to inevitable mortality.
E-bok
PDF, Engelska, 2013708 kr
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The number of children with allergies is astounding-nearly one child in six is said to suffer from some sort of allergy. The problems of these allergic children can be as mild as occasional attacks of hay fever or as severe as disfiguring eczema and life-threatening bronchial asthma. In addition to the obvious health problems associated with having allergies, affected children may experience recurring colds, painful ear infections, and other allergy linked conditions, all of which cause frequent school absences. Childhood allergies affect school performance adversely; they may be instrumental in reducing attention span, and they are certainly a major social, psychologi cal, and financial burden for children and their parents. This book is a complete guide to childhood allergies presented in simple jargon-free language. It provides parents with comprehensive, up-to-date, and practical information and advice on how to help their allergic children. It identifies the many allergic symptoms, tells what they look like, how prevalent they are, what causes them, and what to do about them. It outlines steps parents can take to help their children understand, manage, and control their allergies. Its goal is to help parents and children cope effectively with a major childhood problem.
Inbunden, Engelska, 2014
2 221 kr
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Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals.
E-bok
PDF, Engelska, 20142 194 kr
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Diseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment, 2nd Edition, offers the definitive source of information about the basic science of the sinuses and the clinical approach to sinusitis. Since the widely praised publication of the first edition, understanding of sinus disease has changed dramatically, mainly as a result of recent developments and new discoveries in the field of immunology. This updated and expanded edition is divided into sections addressing, separately, the pathogenesis, clinical presentation, medical and surgical management of acute and chronic rhinosinusitis. Special entities such as autoimmune-related sinusitis, allergy and sinusitis, and aspirin-exacerbated respiratory disease are discussed in separate chapters. The role of immunodeficiency is also addressed. The management section has been fully updated to incorporate new medical modalities and surgical procedures. Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals. Internists, pediatricians, allergists, otolaryngologists and infectious disease specialists will find the book to be an invaluable, comprehensive reference. Physician assistants and nurse practitioners who work with specialists who treat sinus disease will also benefit from the book.
Häftad, Engelska, 2016
1 723 kr
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Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals.