Peroxisome Proliferator-Activated Receptors

Discovery and Recent Advances

AvJihan A. Youssef,Mostafa Z. Badr

Häftad, Engelska, 2015

1 167 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Fler format och utgåvor

Inbunden

1 589 kr

Beskrivning

All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity.

Produktinformation

Utgivningsdatum:2015-05-22
Mått:155 x 235 x 9 mm
Vikt:236 g
Format:Häftad
Språk:Engelska
Antal sidor:137
Förlag:Humana Press Inc.
ISBN:9781627038867

Utforska kategorier

Biokemi inom Naturvetenskap och teknik

Innehållsförteckning

Introduction.- History of PPAR Discovery: Peroxisomes.- Peroxisomal biogenesis and diseases.- Peroxisome proliferation.- Peroxisome Proliferator-Activated Receptors: Chromosomal location and gene polymorphism.- Protein structure.- PPAR Ligands: Endogenous ligands.- Exogenous PPAR modulators.- Tissue Distribution and Versatile Functions of PPARs: Neurological functions of PPARs.- PPARs and the cardiovascular system.- PPARs in pulmonary physiology and disease.- Gastrointestinal roles of PPARs.- PPAR functions in the liver.- Roles of PPARs in the pancreas.- PPARs in the urinary tract physiology and pathophysiology.- PPARs in the reproductive system.- Bone metabolism and PPARs.- Roles of PPARs in skeletal muscle biology.- Skin PPARs.- PPARs and Drug Metabolism.- Molecular Aspects of PPAR Actions: Posttranslational control of PPARs.- Mechanism of action.- Animal Models in PPAR Research.- Safety of PPAR Agonists.- The Future of PPAR Research.