Tumor Microenvironment

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

• Novel techniques to study the bone-tumor microenvironment.- An emerging model for cancer development from a tumor.- microenvironment perspective in mice and humans.- Effects of Exercise on the Tumour Microenvironment.- Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment.- Multimodal molecular imaging of the tumour microenvironment.-  Necrosis in the tumor microenvironment and its role in cancer recurrence.- The Multifaceted Effects of Autophagy on the Tumor Microenvironment.- The Sociobiology of Brain Tumors.- Tumor microenvironment conditioning by abortive lytic replication of oncogenic γ-herpesviruses.- The microbiome as a component of the tumor microenvironment.- Index.