Synthetic Biology of Yeasts

Farshad Darvishi Harzevili is a faculty member of Alzahra University and University of Maragheh, Iran and head of the microbial biotechnology and bioprocess engineering (MBBE) group. He is mainly interested in the biotechnological and environmental applications of yeasts to the production of biotechnologically valuable products. He is also interested in the expression of heterologous proteins, metabolic engineering, and synthetic biology of yeasts. Professor Darvishi's research group is active in the following areas: 1) New and powerful methods for strain characterization (X-Omics such as genomics, metagenomics, transcriptomics, proteomics, metabolomics, lipidomics, fluxomics) and improvement (such as metabolic engineering, reverse metabolic engineering, adaptive laboratory evolution (ALE), systems biology, synthetic biology). 2) Heterologous protein expression in Saccharomyces cerevisiae, Yarrowia lipolytica, Pichia pastoris and other nonconventional yeasts. 3) Production of biotechnologically valuable products from renewable sources and wastes. 4) Isolation and biodiversity study of yeasts.

• Computational Prediction Tools for Synthetic Biology Components.- Computational Tools for Pathway Prediction and Design.- Computational Tools for Metabolic Modeling.- Computational Tools for Strain Optimization.- New Tools for the Synthesis of Standardized Biobricks.- Assembly of Standardized Biobricks and Construction of Pathways.- New and Powerful Genome Editing Methods.- Optimization of Synthetic Pathways.- Engineering of Yeast Consortia. Synthetic Biology of Yeasts for Pharmaceuticals Production.