Cellular and Molecular Aspects of Ageing

Häftad, Engelska, 2025

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Beskrivning

Unravelling cellular and molecular aspects of ageing is crucial for the unanswered questions about ageing and for guiding interventions such as changes in lifestyle, senolytic (kills senescent cells), and senomorphic (interrupts deleterious intercellular communication) therapies.

Produktinformation

Utgivningsdatum:2025-04-05
Mått:155 x 235 x 10 mm
Vikt:260 g
Format:Häftad
Språk:Engelska
Antal sidor:158
Förlag:Springer International Publishing AG
ISBN:9783031550249

Utforska kategorier

Onkologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Mer om författaren

Valquiria Bueno has a background in Biology and a Post Doc in Immunology by The University of Oxford. As an Associate Professor at UNIFESP since 2006 and she has been working in the Ageing issue for more than one decade. In association with researchers of the Ageing field around the world she has published two other books: "The Ageing Immune System and Health" edited by Valquiria Bueno, Janet M Lord and Thomas Jackson and "Healthy Longevity and Immune System" edited by Valquiria Bueno and Graham Pawelec. Her main interest is on how the ageing process interferes with the immune system function and what are the consequences of it for the older individuals. She has been supported with Brazilian (FAPESP, CAPES, CNPq), British Council and Newton Fund grants for the study of the Ageing process and changes occurring in he Immune System.

Innehållsförteckning

1. Introduction: Daniela Frasca & Valquiria Bueno.- 2. Cellular Senescence: Laura Haynes.- 3. Genomic instability: Carlos López-Otín.- 4. Telomeres:Rodrigo do Tocantins C.S.Rodrigues.- 5. Epigenetic: Miriam Galvonas Jasiulionis.- 6. Proteostasis: Ana Maria Cuervo.- 7. Deregulated nutrient-sensing: Pedro Manoel M.M.Vieira.- 8. Mitochondria/Oxidative Stress: Tiago Rodrigues.- 9. Stem cell exhaustion: Michael D Milsom.- 10. Cell-to-cell communication: Ana O'Loghlen.- 11. Senescence-associated secretory phenotype (SASP): Janet M Lord.