Areas of intensive livestock production are currently facing a significant transformation process. In the context of climate change, the planetary boundaries, political conflicts and crises as well as a growing population, sustainable, effective and resilient agrifood systems need to be established. To achieve this goal, society, politics, the economy, agriculture and science are equally challenged. Only with a holistic, systemic and participatory strategy, a transformation of the existing system can be achieved. This book analyses the current transition processes as well as its drivers and barriers and gives examples for new integrated strategies, concepts, business models and developments for the livestock sector. Finally, the book indicates fields of action for the establishment of sustainable livestock farming. The book will appeal to stakeholders in science, society, economy, policy, agricultural industry, stakeholders in veterinary practice and agriculture.