Fc Receptors

Inbunden, Engelska, 2014

Del 382 i serien Current Topics in Microbiology and Immunology

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Beskrivning

Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection.

Produktinformation

Utgivningsdatum:2014-08-25
Mått:155 x 235 x 30 mm
Vikt:822 g
Format:Inbunden
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:424
Upplaga:2014
Förlag:Springer International Publishing AG
ISBN:9783319079103

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

Innehållsförteckning

The Old but New IgM Fc Receptor (FcμR).- Emerging Roles for FCRL Family Members in Lymphocyte Biology and Disease.- Intracellular antibody immunity and the cytosolic Fc receptor TRIM21.- Computational modeling of the main signaling pathways involved in mast cell activation.- Calcium channels in FcR signaling.- Regulation of FcεRI signaling by lipid phosphatases.- Fc Receptors as Adaptive Immunoreceptors.- Glycosylation and Fc Receptors.- Antibodies as natural adjuvants.- IgA, IgA receptors and their anti-inflammatory properties.- Humanized mice to study FcγR function.- FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions.- Human FcR polymorphism and disease.- Bridging auto-antibodies and arthritis; the role of Fc Receptors.- The FcγR of humans and non-human primates and their interaction with IgG: Implications for induction of inflammation, resistance to infection and the use of therapeutic monoclonal antibodies.- FcgRIIB as a key determinant of agonistic antibody efficacy.- Fc receptor dependent mechanisms of monoclonal antibody therapy of cancer; professionals at work.- Sweet and Sour: The role of glycosylation for the anti-inflammatory activity of immunoglobulin G.