This book constitutes the thoroughly refereedpost-conference proceedings of the 10th International Conference on Large-ScaleScientific Computations, LSSC 2015, held in Sozopol, Bulgaria, in June 2015.The 49 revised full papers presented were carefullyreviewed and selected from 64 submissions. The general theme for LSSC 2015 wasLarge-Scale Scientific Computing with a particular focus on the organizedspecial sessions: enabling exascale computation; control and uncertain systems;computational microelectronics - from monte carlo to deterministic approaches;numerical methods for multiphysics problems; large-scale models: numericalmethods, parallel computations and applications; mathematical modeling andanalysis of PDEs describing physical problems; a posteriori error control anditerative methods for maxwell type problems; efficient algorithms for hybridHPC systems; multilevel methods on graphs; and applications of metaheuristicsto large-scale problems.
