Mechanical Ventilation in Critically Ill Cancer Patients

Antonio M. Esquinas, MD, PhD, is a member of staff on the Intensive Care Unit and Non-invasive Ventilatory Unit at Hospital General Universitario Morales Meseguer, Murcia, Spain. Prior to taking up this position in January 2013, he worked in the Departments of Anesthesiology, Critical Care, and Pain Medicine at Sapienza University of Rome, Italy. Dr. Esquinas is a Fellow of the College of Chest Physicians and an International Fellow of the American Association of Respiratory Care. He is Director of the International School of Non-invasive Mechanical Ventilation and President of the International Association of NIV and the Ibero-American  Association of  Bioethics in NIV. He is the author of well over 700 scientific publications, including almost 400 articles and 32 books.S. Egbert Pravinkumar, MD, FRCP, EDIC, is Professor and Associate Medical Director, Department of Critical Care, Division of Anesthesiology and Critical Care, The Universityof Texas MD Anderson Cancer Center, Houston, TX, USA. Dr. Pravinkumar completed his medical degree at Stanley Medical College and University Hospital, University of Madras, Madras, India and subsequently became a Member (1996) and then Fellow (2004) of the Royal College of Physicians of Ireland (Pulmonary Medicine/Internal Medicine). In 2006 he became a Fellow of the American College of Chest Physicians (Pulmonary/Critical Care Medicine). He is the author of 17 articles in peer-reviewed international journals.Ayman O. Soubani, MD, is Professor of Medicine at Wayne State University School of Medicine, Detroit, MI, USA. He is Service Chief of the Pulmonary and Critical Care Section at Karmanos Cancer Center in Detroit and Medical Director, Medical ICU, Harper University Hospital, Detroit. Dr. Soubani has appeared in both Best Doctors of America and America’s Top Doctors. He holds various professional appointments and is a past president of The Michigan Thoracic Society. Dr. Soubani is a member of the editorial boards of Respiration and The Open Transplantation Journal, and a reviewer for numerous journals. He is the author of 84 peer-reviewed journal articles.

“This book is devoted to the identification and management of respiratory complications in critically ill cancer patients. … Critical care providers encountering patients with advanced malignancy and multimodal therapy are an appropriate audience for this international work. … This book provides effective background on mechanical pulmonary support and the challenges of oncology patients.” (David J. Dries, Doody's Book Reviews, April, 2018)

• Part I. Background and Therapeutic Procedures in Critically Ill Cancer Patients.- Epidemiology of Acute Respiratory Failure.- Acute  Respiratory Failure in Different Settings.- Chemotherapy.- Radiation Therapy.- Blood Marrow Transplantation.- Bronchoscopy.- Non-bronchoscopic Procedures.- Invasive and Interventional Procedures.- Part II. Invasive Mechanical Ventilation.- Rationale.- Mechanical Ventilatory Modes.- Part III. Non-invasive Mechanical Ventilation.- Nasal High-Flow System.- Devices.- Continuous Positive Airway Pressure (CPAP).- Bilevel Positive Airway Pressure.- Indications and Contraindications.- Determinants of Success or Failure.- NIV Outcome Decision Algorithm.- Part IV. Postoperative Mechanical Ventilation.- General Postoperative Complications.- Mechanical Ventilation After Neurosurgery.- Mechanical Ventilation After Cardiothoracic Surgery.- Mechanical Ventilation After Thoracic Surgery.- Mechanical Ventilation After Abdominal Surgery.- Mechanical Ventilation AfterOrthopedic Surgery.- Part V. Withdrawal from Mechanical Ventilation Support.- Weaning from Mechanical Ventilation.- Tracheotomy.- Analgesia/Sedation.- Venous Thromboembolic and Gastrointestinal Prophylaxis.- Chest Physiotherapy.- Nutrition.- Long-Term Mechanical Ventilation.- Part VI. Palliative Ventilatory Support in Cancer Critical Care.- Palliative Care.- Avoidance of Endotracheal Intubation.- End-of-life Care. Part VII. Healthcare Resource Utilization and Organizational Support in Cancer Critical Care.- Organization of Ventilatory Support.- Healthcare Resources Ventilatory Support.- Quality-of-Life Ventilatory Support.- Mechanical Ventilation: Current Evidence and Evidence-Based Practice.