Hormones, Metabolism and the Benefits of Exercise

Bruce Spiegelman is a Professor of Cancer Biology at Harvard Medical School and a Stanley J. Korsmeyer Professor of Cell Biology and Medicine

• Introduction.- Human brown adipose tissue plasticity: hormonal and environmental manipulation.- The energy sensor AMPK: Adaptations to exercise, nutritional and hormonal signals.- Plasma steroids and cardiorespiratory fitness response to regular exercise.- Sending the signal: Muscle glycogen availability as a regulator of training adaptation.- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle.- Skeletal muscle microRNAs: Roles in differentiation, disease and exercise.- Tryptophan-kynurenine metabolites in exercise and mental health.- FNDC5/irisin - their role in the nervous system and as a mediator for beneficial effects of exercise on the brain.