Sigma Receptors: Their Role in Disease and as Therapeutic Targets

Häftad, Engelska, 2018

Del 964 i serien Advances in Experimental Medicine and Biology

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Beskrivning

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets.

Produktinformation

Utgivningsdatum:2018-06-13
Mått:178 x 254 x 17 mm
Vikt:693 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:312
Förlag:Springer International Publishing AG
ISBN:9783319843353

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Innehållsförteckning

Foreword.- Chap. 1 Anti-depressant functions of sigma receptor 1.- Chap. 2 Parkinsonism.- Chap. 3 New ligands for sigma receptors and studies of ligand binding sites.- Chap. 4 σR1 and neurite elongation.- Chap. 5 Studies of σR1 in ALS, photaffinity probes and oxidative stress.- Chap. 6 σR1: Pharmacology and protective effects.- Chap. 7 Anti-stroke and anti-excitotoxicity.- Chap. 8 σR1 as a molecular chaperone.- Chap. 9 The potential role of σR1 as a neuroprotective.- Chap. 10 Studies of σR1 and effects on VGCC (calcium channels).- Chap. 11 The role of σR1 in retinal neuroprotection.- Index.