Asymmetric Cell Division in Development, Differentiation and Cancer

Häftad, Engelska, 2018

Del i serien Results and Problems in Cell Differentiation

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Beskrivning

Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.

Produktinformation

Utgivningsdatum:2018-07-21
Mått:155 x 235 x 24 mm
Vikt:645 g
Format:Häftad
Språk:Engelska
Serie:Results and Problems in Cell Differentiation
Antal sidor:421
Förlag:Springer International Publishing AG
ISBN:9783319850771

Utforska kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Innehållsförteckning

1 Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach.- 2 Spatiotemporal models of asymmetric cell division cycle in Caulobacter crescentus.- 3 Intrinsic and extrinsic determinants linking spindle pole fate, spindle polarity and asymmetric cell division in the budding yeast S. cerevisiae.- 4 Wnt signaling polarizes C. elegans asymmetric cell divisions during development.- 5 Asymmetric cell division in the one-cell C.elegans embryo: multiple steps to generate cell size asymmetry.- 6 Size matters: how C. elegans asymmetric divisions regulate apoptosis.- 7 The midbody and its remnant in cell polarization and asymmetric cell division.- 8 Drosophila melanogaster neuroblasts: a model for asymmetric stem cell divisions.- 9 Asymmetric divisions in oogenesis.- 10 Asymmetric localization and distribution of factors determining cell fate during early development of Xenopus laevis.- 11 Asymmetries in cell division, cell size and furrowing in the Xenopuslaevis embryo.- 12 Asymmetric and unequal cell divisions in ascidian embryos.- 13 Asymmetries and symmetries in the mouse oocyte and zygote.- 14 Symmetry does not come for free – cellular mechanisms to achieve a symmetric cell division.- 15 A Comparative Perspective on Wnt/β-catenin Signalling in Cell Fate Determination.- 16 Extracellular regulation of the mitotic spindle and fate determinants driving asymmetric cell division.- 17 Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells.- 18 Molecular programs underlying asymmetric stem cell division and their disruption in malignancy.