Edward R. Laws, Jr., MD, FACS, FAANSDepartment of Neurosurgery Brigham & Women's HospitalBoston, MA Aaron Cohen-Gadol MD, MSc.Department of NeurosurgeryIndianapolis Methodist Hospital Indianapolis, INTheodore H. SchwartzProfessor of Neurosurgery, Otolaryngology and NeuroscienceDavid and Ursel Barnes Professor of Minimally Invasive NeurosurgeryDirector, Anterior Skull Base and Pituitary SurgeryLaboratory for Epilepsy Research and ImagingWeill Cornell Medical CollegeNew York Presbyterian Hospital New York, NYJason P. Sheehan M.D., Ph.D.Department of Radiation OncologyDepartment of Neurological SurgeryUniversity of Virginia Charlottesville, Virginia USA

“Every chapter is written by a well-known and established expert in the field. Many of these contributors share 'pearls' of wisdom that has been gained over many decades of clinical experience. … The book is a useful addition to the library of all surgeons who deal with skull base cranial surgery, and provides outstanding information and reference sources for complex skull base procedures amenable to the transsphenoidal approach.” (David S. Baskin, Neurosurgery, Vol. 83 (03), September, 2018)​

• Evolution of pituitary surgery and the transsphenoidal approach.- The History of Trans-sphenoidal Surgery for Pituitary Tumors.- Principles and Pitfalls of Anesthesia for Transsphenoidal Surgery.- Operative Indications and Pitfalls in Patient Selection for Surgery of Pituitary Tumors.- The Perioperative and Postoperative Care for Pituitary Patients.- Neuro-Ophthalmology of Pituitary Tumors.- Rhinologic evaluation of patients undergoing transsphenoidal surgery.- Imaging of the Sella and Parasellar Region.- Classification, Pathobiology, Molecular Markers, and Intraoperative Pathology.- Surgical Anatomy of the Sellar Region.- Combined Hybrid Microscopic and Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation, and Technique.- Transcranial Approaches to the Sellar and Parasellar Area.- Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation and Technique.- 3-dimensional Endoscopy for Skull Base Surgery.- Endoscopic Transsphenoidal Pituitary Surgery: Results And Complications.- Intraoperative imaging for pituitary surgery.- Closure Methods Following Transsphenoidal Surgery.- Complications with Transsphenoidal Surgery: A Review.- Rhinological Complications: Avoidance and Management.- Medical Management for Pituitary Adenoma Patients.- Transsphenoidal Surgery for Recurrent Pituitary Disease.- Transsphenoidal Surgery for Craniopharyngiomas.- Transsphenoidal Surgery for Cushing’s Disease.- Transsphenoidal surgery for acromegaly.- Transsphenoidal Surgery for Prolactinomas.- Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas.- Pituitary tumors in pediatric patients.- Pituitary apoplexy.- Anatomical Approaches to Giant Pituitary Tumors.- Postoperative Management of Patients Following Transsphenoidal Surgery.- Stereotactic Radiosurgery for Pituitary Adenomas.- Cytotoxic chemotherapy and targeted therapy for aggressive pituitary tumors.- Quality of life in patients with pituitary adenomas.

Edward R. Laws, Jr., MD, FACS, FAANSDepartment of Neurosurgery Brigham & Women's HospitalBoston, MA Aaron Cohen-Gadol MD, MSc.Department of NeurosurgeryIndianapolis Methodist Hospital Indianapolis, INTheodore H. SchwartzProfessor of Neurosurgery, Otolaryngology and NeuroscienceDavid and Ursel Barnes Professor of Minimally Invasive NeurosurgeryDirector, Anterior Skull Base and Pituitary SurgeryLaboratory for Epilepsy Research and ImagingWeill Cornell Medical CollegeNew York Presbyterian Hospital New York, NYJason P. Sheehan M.D., Ph.D.Department of Radiation OncologyDepartment of Neurological SurgeryUniversity of Virginia Charlottesville, Virginia USA

“Every chapter is written by a well-known and established expert in the field. Many of these contributors share 'pearls' of wisdom that has been gained over many decades of clinical experience. … The book is a useful addition to the library of all surgeons who deal with skull base cranial surgery, and provides outstanding information and reference sources for complex skull base procedures amenable to the transsphenoidal approach.” (David S. Baskin, Neurosurgery, Vol. 83 (03), September, 2018)​

• Evolution of pituitary surgery and the transsphenoidal approach.- The History of Trans-sphenoidal Surgery for Pituitary Tumors.- Principles and Pitfalls of Anesthesia for Transsphenoidal Surgery.- Operative Indications and Pitfalls in Patient Selection for Surgery of Pituitary Tumors.- The Perioperative and Postoperative Care for Pituitary Patients.- Neuro-Ophthalmology of Pituitary Tumors.- Rhinologic evaluation of patients undergoing transsphenoidal surgery.- Imaging of the Sella and Parasellar Region.- Classification, Pathobiology, Molecular Markers, and Intraoperative Pathology.- Surgical Anatomy of the Sellar Region.- Combined Hybrid Microscopic and Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation, and Technique.- Transcranial Approaches to the Sellar and Parasellar Area.- Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation and Technique.- 3-dimensional Endoscopy for Skull Base Surgery.- Endoscopic Transsphenoidal Pituitary Surgery: Results And Complications.- Intraoperative imaging for pituitary surgery.- Closure Methods Following Transsphenoidal Surgery.- Complications with Transsphenoidal Surgery: A Review.- Rhinological Complications: Avoidance and Management.- Medical Management for Pituitary Adenoma Patients.- Transsphenoidal Surgery for Recurrent Pituitary Disease.- Transsphenoidal Surgery for Craniopharyngiomas.- Transsphenoidal Surgery for Cushing’s Disease.- Transsphenoidal surgery for acromegaly.- Transsphenoidal Surgery for Prolactinomas.- Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas.- Pituitary tumors in pediatric patients.- Pituitary apoplexy.- Anatomical Approaches to Giant Pituitary Tumors.- Postoperative Management of Patients Following Transsphenoidal Surgery.- Stereotactic Radiosurgery for Pituitary Adenomas.- Cytotoxic chemotherapy and targeted therapy for aggressive pituitary tumors.- Quality of life in patients with pituitary adenomas.

Edward R. Laws, Jr., MD, FACS, FAANSDepartment of Neurosurgery Brigham & Women's HospitalBoston, MA Aaron Cohen-Gadol MD, MSc.Department of NeurosurgeryIndianapolis Methodist Hospital Indianapolis, INTheodore H. SchwartzProfessor of Neurosurgery, Otolaryngology and NeuroscienceDavid and Ursel Barnes Professor of Minimally Invasive NeurosurgeryDirector, Anterior Skull Base and Pituitary SurgeryLaboratory for Epilepsy Research and ImagingWeill Cornell Medical CollegeNew York Presbyterian Hospital New York, NYJason P. Sheehan M.D., Ph.D.Department of Radiation OncologyDepartment of Neurological SurgeryUniversity of Virginia Charlottesville, Virginia USA

“Every chapter is written by a well-known and established expert in the field. Many of these contributors share 'pearls' of wisdom that has been gained over many decades of clinical experience. … The book is a useful addition to the library of all surgeons who deal with skull base cranial surgery, and provides outstanding information and reference sources for complex skull base procedures amenable to the transsphenoidal approach.” (David S. Baskin, Neurosurgery, Vol. 83 (03), September, 2018)​

• Evolution of pituitary surgery and the transsphenoidal approach.- The History of Trans-sphenoidal Surgery for Pituitary Tumors.- Principles and Pitfalls of Anesthesia for Transsphenoidal Surgery.- Operative Indications and Pitfalls in Patient Selection for Surgery of Pituitary Tumors.- The Perioperative and Postoperative Care for Pituitary Patients.- Neuro-Ophthalmology of Pituitary Tumors.- Rhinologic evaluation of patients undergoing transsphenoidal surgery.- Imaging of the Sella and Parasellar Region.- Classification, Pathobiology, Molecular Markers, and Intraoperative Pathology.- Surgical Anatomy of the Sellar Region.- Combined Hybrid Microscopic and Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation, and Technique.- Transcranial Approaches to the Sellar and Parasellar Area.- Endoscopic Transsphenoidal Surgery: Anatomy, Instrumentation and Technique.- 3-dimensional Endoscopy for Skull Base Surgery.- Endoscopic Transsphenoidal Pituitary Surgery: Results And Complications.- Intraoperative imaging for pituitary surgery.- Closure Methods Following Transsphenoidal Surgery.- Complications with Transsphenoidal Surgery: A Review.- Rhinological Complications: Avoidance and Management.- Medical Management for Pituitary Adenoma Patients.- Transsphenoidal Surgery for Recurrent Pituitary Disease.- Transsphenoidal Surgery for Craniopharyngiomas.- Transsphenoidal Surgery for Cushing’s Disease.- Transsphenoidal surgery for acromegaly.- Transsphenoidal Surgery for Prolactinomas.- Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas.- Pituitary tumors in pediatric patients.- Pituitary apoplexy.- Anatomical Approaches to Giant Pituitary Tumors.- Postoperative Management of Patients Following Transsphenoidal Surgery.- Stereotactic Radiosurgery for Pituitary Adenomas.- Cytotoxic chemotherapy and targeted therapy for aggressive pituitary tumors.- Quality of life in patients with pituitary adenomas.